不同灸法对胃肠道肿瘤化疗患者癌因性疲乏的影响  

Effects of different moxibustion methods on cancer-related fatigue in patients with gastrointestinal cancer undergoing chemotherapy

作　　者：朱小燕 胡颖颖 ZHU Xiaoyan;HU Yingying(Department of Oncology,Jinhua Traditional Chinese Medicine Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine,Jinhua,Zhejiang 310017,China)

机构地区：[1]浙江中医药大学附属金华中医院肿瘤科,浙江金华310017

出　　处：《中华全科医学》2024年第6期1051-1054,共4页Chinese Journal of General Practice

基　　金：浙江省中医药科技计划项目(2020ZB283)。

摘　　要：目的比较不同艾灸方法对胃肠道肿瘤患者化疗中癌因性疲乏的影响,为提高胃肠道肿瘤辅助治疗效果提供依据。方法选取2021年1月—2023年4月在浙江中医药大学附属金华中医院行术后化疗的胃肠道恶性肿瘤患者108例,根据随机数字表法分为常规组、传统组和灸温组各36例。比较3组干预前后癌症疲乏程度、生活质量及血常规。结果干预后,传统组和温灸组癌因性疲乏量表各维度(情感、躯体、认知)评分及量表总分均明显低于常规组(P<0.05);干预后,传统组QLQ-C30量表各评分(身体、角色、情感、认知、社会、整体生活质量、疲乏感、恶心呕吐、疼痛、呼吸困难、睡眠障碍、食欲减退、便秘、腹泻、经济困难感知)均明显优于常规组,且灸温组均明显优于传统组(P<0.05);干预后,传统组红细胞和血小板计数分别为(4.98±1.63)×10^(12)/L、(141.96±27.85)×10^(9)/L,灸温组分别为(5.65±0.74)×10^(12)/L、(149.75±26.89)×10^(9)/L,均明显高于常规组的(4.15±1.52)×10^(12)/L、(133.76±25.77)×10^(9)/L(F=4.255、8.175,均P<0.05)。结论艾灸法能有效缓解胃肠道肿瘤患者化疗期间癌因性疲乏症状,改善血常规水平,提高生活质量,灸温在41~42℃更有利于提高艾灸疗效。Objective To compare the effects of different moxibustion methods on cancer-induced fatigue in patients with gastrointestinal tumors during chemotherapy,and provide evidence for improving the efficacy of adjuvant therapy for gastrointestinal tumors.Methods A total of 108 patients with gastrointestinal malignancies who received postoperative chemotherapy in Jinhua Traditional Chinese Medicine Hospital from January 2021 to April 2023 were selected and randomly divided into the conventional group,the traditional group,and the moxibustion warm group with 36 cases in each group according to random number table method.Cancer fatigue degree,quality of life,and blood routine were compared before and after intervention.Results After the intervention,the scores of all dimensions(emotional,physical,and cognitive)and the total score of the cancer fatigue scale in the traditional group and the warm moxibustion group were significantly lower than those in the conventional group(P<0.05).After the intervention,all QLQ-C30 scales(physical,role,emotional,cognitive,social,overall quality of life,fatigue,nausea and vomiting,pain,dyspnea,sleep disorders,appetite loss,constipation,diarrhea,and perceived economic hardship)in the traditional group were significantly better than those in the conventional group,and the scores in the moxibustion warm group were significantly better than those in the traditional group(P<0.05).After the intervention,red blood cell count and platelet count were(4.98±1.63)×10^(12)/L and(141.96±27.85)×10^(9)/L in the traditional group,and(5.65±0.74)×10^(12)/L and(149.75±26.89)×10^(9)/L in moxibustion warm group,respectively,which were significantly higher than those in the conventional group(4.15±1.52)×10^(12)/L and(133.76±25.77)×10^(9)/L(F=4.255,8.175,both P<0.05).Conclusion Moxibustion can effectively relieve the symptoms of cancer-related fatigue in patients with gastrointestinal tumors during chemotherapy,and improve the level of blood routine and their quality of life.Moxibustion applied at 41-

关 键 词：艾灸 胃肠道肿瘤 灸温 癌因性疲乏 生活质量 

分 类 号：R735[医药卫生—肿瘤] R245.8[医药卫生—临床医学]