Risk Factors of Enternal Nutrition Intolerance in Septic Patients:A Case-control Study  

作　　者：Li-zhu WANG Yan XIANG Qian LI Yi-rong ZHU Jue FANG Xiao-dan LU Zhao-cai ZHANG 

机构地区：[1]Department of Nursing,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China [2]Department of Critical Care Medicine,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China [3]Key Laboratory of the Diagnosis and Treatment for Severe Trauma and Burn of Zhejiang Province,Hangzhou 310009,China [4]Zhejiang Province Clinical Research Center for Emergency and Critical Care Medicine,Hangzhou 310009,China

出　　处：《Current Medical Science》2024年第2期328-332,共5页当代医学科学（英文）

基　　金：supported by the National Key Research and Development Program of China(No.2021YFC2501800);the National Natural Science Foundation of China(Nos.82272182 and 82072202);the Zhejiang Provincial Natural Science Foundation of China(No.LHDMD22H02001);the Zhejiang University Horizontal Program(No.K-Horizontal 20202295).

摘　　要：Objective:This study aimed to investigate the incidence of enteral nutrition intolerance(ENI)in patients with sepsis and explore potential risk factors.Methods:A case-control study was conducted in patients with sepsis who were receiving enteral nutrition(EN)at a tertiary hospital in China.The included patients were divided into the ENI group and the non-ENI group.Univariate and multivariate analyses were performed to identify the risk factors for ENI.Results:A total of 859 patients were included in the study.Among them,288(33.53%)patients experienced symptoms of ENI,including diarrhea,vomiting,bloating,and gastric retention.Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H(APACHE H)score,thoracocentesis,and usage of cardiotonic drugs(namely,inotropes)were independent predictors of the ENI.Conclusion:The incidence of ENI is relatively high in patients with sepsis,especially in those who have higher APACHE H scores,have undergone thoracocentesis,and have received inotropes.

关 键 词：SEPSIS enteral nutrition intolerance influencing factor 

分 类 号：R515.3[医药卫生—内科学]