全自动凝血检测流水线在高通量标本检测中的临床应用评估  

Evaluation of clinical application of automatic coagulation detection assembly line in high-throughput specimen detection

作　　者：吴蕙 孙林 顾梅秀 郭奕超 王冲 王蓓丽 潘柏申 郭玮 WU Hui;SUN Lin;GU Meixiu;GUO Yichao;WANG Chong;WANG Beili;PAN Baishen;GUO Wei(Department of Clinical Laboratory,Zhongshan Hospital Affiliated to Fudan University,Shanghai 200032,China;Department of Clinical Laboratory,Wusong Central Hospital of Baoshan District,Shanghai 201900,China;Department of Clinical Laboratory,Xiamen Branch,Zhongshan Hospital Affiliated to Fudan University,Xiamen,Fujian 361015,China)

机构地区：[1]复旦大学附属中山医院检验科,上海200032 [2]宝山区吴淞中心医院检验科,上海201900 [3]复旦大学附属中山医院厦门医院检验科,福建厦门361015

出　　处：《国际检验医学杂志》2024年第12期1416-1418,1424,共4页International Journal of Laboratory Medicine

基　　金：国家自然科学基金面上项目(81972000,82172348);国家自然科学基金青年科学基金项目(81902139);上海市临床重点专科建设项目(shslczdzk03302);厦门市医疗卫生重点项目(YDZX20193502000002);上海市宝山区医学重点专科项目(BSZK-2023-A18);复旦大学附属中山医院临床研究专项基金(2020ZSLC54,2021ZSGG08)。

摘　　要：目的评估全自动凝血检测流水线在高通量标本检测中的临床应用。方法收集2021年6-8月复旦大学附属中山医院的枸橼酸钠抗凝标本相关信息,包括标本采集时间、接收时间、仪器吸样时间、检测完成时间和是否通过自动审核等内容,比较全自动凝血检测流水线安装前后标本预处理时间、检测时间、标本周转时间(TAT),对全自动凝血检测流水线检测速度进行评估。结果全自动凝血检测流水线每小时预计可检测650~900个标本,比浊法项目数量增多会减慢仪器检测速度。全自动凝血检测流水线检测门诊和病房的标本预处理时间及检测时间明显短于单机检测,差异均有统计学意义(P<0.05)。全自动凝血检测流水线能够缩短TAT(P<0.05)。应用全自动凝血检测流水线后,自动审核率为25.6%。结论全自动凝血检测流水线适用于实验室高通量标本检测。与单机检测相比,全自动凝血检测流水线能够缩短TAT和检测时间,有助于减轻实验室人员的工作压力。Objective To evaluate the clinical application of automatic coagulation detection assembly line in high-throughput specimen detection.Methods The relevant information of sodium citrate anticoagulation samples in Zhongshan Hospital Affiliated to Fudan University from June to August 2021 was collected,including sample collection time,receiving time,instrument sucking time,test completion time,and whether it passed autoverification or not.The sample pretreatment time,testing time and turnaround time(TAT)of the automatic coagulation detection assembly line were compared before and after installation,and the detection speed of the automatic coagulation detection assembly line was evaluated.Results The automatic coagulation detection line was expected to detect 650-900 samples per hour.The increase in the number of turbidimetric tests would slow down the detection speed of the instrument.Automatic coagulation detection assembly line test specimen to clinic and ward of pretreatment time and testing time were shorter than single detection,the differences were statistically significant(P<0.05).The automatic coagulation detection assembly line could shorten TAT(P<0.05).After the application of automatic coagulation detection assembly line,the autoverification rate was 25.6%.Conclusion The automatic coagulation detection assembly line is suitable for high-throughput specimen detection in laboratory.Compared with stand-alone coagulation detection,the automatic coagulation detection assembly line could shorten TAT and testing time,and help to reduce the work pressure of laboratory personnel.

关 键 词：全自动凝血检测流水线 高通量标本 标本周转时间 

分 类 号：R-331[医药卫生]