对比分析不同矫治方法对青少年正畸患者唾液趋化因子、龈沟液炎症因子表达及牙周健康的影响  

Comparative Analysis of the Effects of Different Orthodontic Methods on the Expression of Salivary Chemokines,Gingival Crevicular Fluid Inflammatory Factors,and Periodontal Health in Adolescent Orthodontic Patients

作　　者：李敏 回记芳 张岁改 罗虹 牛亦睿[1] LI Min;HUI Ji-fang;ZHANG Sui-gai;LUO Hong;NIU Yi-rui(First Outpatient Department,Xi'an Jiaotong University Stomatological Hospital,Xian,Shaanxi,710000,China;Department of Children's Dental and Facial Development Management,Xi'an Jiaotong University Stomatological Hospital,Xian,Shaanxi,710000,China)

机构地区：[1]西安交通大学口腔医院第一门诊部,陕西西安710000 [2]西安交通大学口腔医院儿童牙颌颜面发育管理专科,陕西西安710000

出　　处：《现代生物医学进展》2024年第10期1921-1925,共5页Progress in Modern Biomedicine

基　　金：陕西省重点研发计划一般项目社会发展领域(2022SF-281)。

摘　　要：目的:对比分析不同矫治方法对青少年正畸患者唾液趋化因子、龈沟液炎症因子表达及牙周健康的影响。方法:选取我院2020年1月到2023年1月收治的100例正畸治疗的青少年患者,应用随机数字表法将其进行回顾性分析,其中30例患者采取Twin-Block矫治器进行治疗,将其分为Twin-Block组,30例患者采取直丝弓矫治器治疗,将其分为直丝弓组,40例患者采取无托槽隐性矫治器治疗,将其分为无托槽组。对比三组患者的矫正满意度,治疗前后唾液趋化因子、龈沟液炎症因子及牙周健康指标水平变化。结果:无托槽组咀嚼功能、美观程度、舒适性、方便程度满意度评分高于Twin-Block组和直丝弓组(P<0.05);矫治半年后,无托槽组CXCL13、CXCL11、CXCL10、CXCL8相关唾液趋化因子水平低于直丝弓组和Twin-Block组,Twin-Block组低于直丝弓组(P<0.05);三组患者矫治半年后,无托槽组IL-1β、TNF-α表达水平低于直丝弓组和Twin-Block组,Twin-Block组低于直丝弓组(P<0.05);矫治半年后,无托槽组CAL、PD、BI、PLI水平低于直丝弓组和Twin-Block组,Twin-Block组低于直丝弓组(P<0.05)。结论:无托槽隐性矫治器在青少年正畸治疗患者满意度优于Twin-Block矫治器和直丝弓矫治器,但无托槽隐性矫治器治疗过程中对患者唾液趋化因子、牙龈雅正反应及牙周健康水平影响较小,临床可依照患者经济情况及对美观程度的要求综合选择。Objective:To compare and analyze the effects of different orthodontic methods on the expression of salivary chemokines,gingival crevicular fluid inflammatory factors,and periodontal health in adolescent orthodontic patients.Methods:A total of100 adolescent patients treated with orthodontic treatment in our hospital from January 2020 to January 2023 were selected.A retrospective analysis was conducted using a random number table method.Among them,30 patients were treated with Twin Block appliances and divided into a Twin Block group.30 patients were treated with a straight wire appliance and divided into a straight wire arch group.40 patients were treated with a non bracket concealed appliance and divided into a non bracket group.Compare the corrective effects of three groups of patients,including changes in salivary chemokines,gingival crevicular fluid inflammatory factors,and periodontal health indicators before and after treatment.Results:Masticatory function,aesthetics,comfort,and convenience satisfaction scores were higher than those in the Twin-Block and straight silk arch groups(P<0.05);After the correction correction,The levels of CXCL13,CXCL11,CXCL10,and CXCL 8 related salivary chemokines in the no-bracket group were lower than those in the straight and Twin-Block groups,The Twin-Block group was lower than the straight silk arch group(P<0.05);After the correction in the three groups of patients,The expression levels of IL-1βand TNF-αin the no-free group were lower than the straight filament arch group and Twin-Block group,The Twin-Block group was lower than the straight silk arch group(P<0.05);After the correction correction,CAL,PD,BI and PLI levels were lower in the no less group than in the straight silk arch and Twin-Block group,The Twin-Block group was lower than that in the straight silk arch group(P<0.05).Conclusion:Invisible bracketless orthodontic appliances in adolescent orthodontic treatment patient satisfaction is better than Twin-Block orthodontic appliances and straight arch orthodontic app

关 键 词：TWIN-BLOCK矫治器 直丝弓矫治器 无托槽隐性矫治器 唾液趋化因子 龈沟液炎症因子 牙周健康 

分 类 号：R783.5[医药卫生—口腔医学] R781.4[医药卫生—临床医学]