大肝癌消融治疗的应用及其进展  

Application and progress of ablation therapy for large liver cancer

作　　者：王震 王震[3] 王硕 张艺琼 于晓玲[1] Wang Zhen;Wang Zhen;Wang Shuo;Zhang Yiqiong;Yu Xiaoling(Department of Interventional Ultrasound,First Medical Center of Chinese PLA General Hospital,Beijing 100039,China;Chinese PLA Medical School,Beijing 100039,China;Department of Interventional Ultrasound,Fifth Medical Center of Chinese PLA General Hospital,Beijing 100039,China)

机构地区：[1]解放军总医院第一医学中心介入超声科,北京100039 [2]解放军医学院,北京100039 [3]解放军总医院第五医学中心介入超声科,北京100039

出　　处：《中华肝脏病杂志》2024年第5期469-473,共5页Chinese Journal of Hepatology

基　　金：国家自然科学基金(82172027)。

摘　　要：原发性肝癌是常见的恶性肿瘤之一,当肿瘤直径≥5 cm时被定义为大肝癌,大肝癌因其自身特点,只有少部分能接受切除手术治疗,因而其非切除手术治疗成为广为关注的热点和难点问题。近年随着消融技术的发展,单独应用消融和消融联合其他方式治疗大肝癌的研究不断深入,取得了较好的临床效果。虽然消融治疗大肝癌的报道很多,但目前并没有规范的治疗指南,在治疗策略方面仍存在争议,现就消融治疗大肝癌的发展、单独及联合消融治疗大肝癌的现状及其相关并发症的防范等方面进行综述。Primary liver cancer is one of the most common malignant tumors.A liver tumor is defined as a large cancer when its diameter is≥5 cm.Resection surgical therapy can be performed only on a small portion of large cancers because of its own features.As a result,non-resection surgical therapy has become a hot and difficult issue of widespread concern.In recent years,with the development of ablation technology,research on the use of ablation alone and ablation combined with other modalities for the treatment of large liver cancer has continued to deepen,and good clinical results have been achieved.Although there are many reports on ablation treatment for large liver cancer,there are currently no standardized treatment guidelines,and there are still controversies about treatment strategies.This article reviews the development of ablation therapy,the current status of single and combined ablation therapy,the prevention of related complications,and other aspects of large liver cancer.

关 键 词：肝细胞癌 消融 治疗 巨大肝癌 并发症 综述 

分 类 号：R735.7[医药卫生—肿瘤]