交感神经兴奋性与醒后脑卒中发生发展的相关性研究  

Study on the correlation between sympathetic nerve excitability and the occurrence and development of wakeup stroke

作　　者：王静[1] 吕俊丽 连红亮 郄新稳 侯娇[1] 王相斌[1] 薛陆明 王苏叶 周慧[1] 尤素伟[1] WANG Jing;LU Junli;LIAN Hongliang(Department of Neurology,Handan Central Hospital,Handan 056001,China)

机构地区：[1]邯郸市中心医院神经内科,056001

出　　处：《临床神经病学杂志》2024年第2期81-85,共5页Journal of Clinical Neurology

基　　金：河北省2022年度医学科学研究课题计划(20220563)。

摘　　要：目的 分析交感神经兴奋性与醒后脑卒中发生发展的相关性。方法 选取2020年7月至2022年1月我院收治的100例急性脑卒中住院患者,依据是否发生醒后脑卒中将患者分为醒后脑卒中组和非醒后脑卒中组。采用Logistic回归分析交感神经兴奋与醒后脑卒中发生发展的关系。结果 多因素分析显示,血压变异性、心率变异性、血糖变异性、电解质紊乱、25-羟维生素D_(3)、尿香草苦杏仁酸、儿茶酚胺是醒后脑卒中发生发展的危险因素(均P<0.05)。结论 交感神经兴奋性与醒后脑卒中发生发展具有相关性,血压变异性、心率变异性、血糖变异性、电解质紊乱、25-羟维生素D3、尿香草苦杏仁酸、儿茶酚胺是醒后脑卒中发生发展的危险因素。Objective To analyze the correlation between sympathetic nerve excitability and the occurrence and development of wake-up stroke.Methods A total of 100 patients with acute stroke admitted to our hospital from July 2020 to January 2022 were selected and divided into wake-up stroke group and non-wake-up stroke group according to whether wake-up stroke occurred.Logistic regression model was established to analyze the relationship between sympathetic excitation and the occurrence and development of wake-up stroke.Results Multivariate analysis showed that blood pressure variability,heart rate variability,blood glucose variability,electrolytes disturbance,25-hydroxyvitamin D_(3)urinary vanilla biter almond acid,and catecholamine were risk factors for the occurrence and development of stroke after waking up(all P<0.05).Conclusions Sympathetic nerve excitability is related to the occurrence and development of stroke after waking up.Blood pressure variability,heart rate variability,blood glucose variability,electrolyte disturbance,25-hydroxyvitamin D,urinary vanilla biter almond acid and catecholamine are risk factors for the occurrence and development of stroke after waking up.

关 键 词：醒后脑卒中 发生发展 交感神经 相关性 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]