血压节律和血压变异性对脑小血管病的影响  

Impact of circadian rhythm of blood pressure and blood pressure variability on cerebral small vessel disease

作　　者：谭沙一君 李路明 刘如 刘逊 何明利 TAN Shayijun;LI Luming;LIU Ru(Lianyungang Clinical College of Nanjing Medical University,Lianyungang 222061,China)

机构地区：[1]南京医科大学连云港临床医学院,222061

出　　处：《临床神经病学杂志》2024年第2期145-148,共4页Journal of Clinical Neurology

基　　金：国家自然科学基金面上项目(81970348)。

摘　　要：当今社会随着人们生活水平的提高和人口老龄化进程加快,脑小血管病已严重危害中老年人的生命健康和生活质量。高血压作为脑小血管病的重要危险因素越来越受到重视。然而,目前在高血压管理中,人们普遍关注血压水平的影响,往往忽视了血压变异性和血压节律的作用。本文阐述了脑小血管病的发病机制以及近年来关于血压变异性和血压节律的研究进展,并指出了深入研究血压变异性和血压节律对脑小血管病发生发展的影响等系列科学问题。Nowadays,with the improvement of people's living standards and the acceleration of the aging process of population,cerebral small vessel disease has seriously endangered the life health and quality of life of the elderly.Hypertension has been paid more and more attention as an important risk factor of cerebral small vessel disease.However,in the management of hypertension,people generally concentrate on the influence of mean arterial pressure,ignoring the role of variability and circadian rhythm of blood pressure nowadays.By expounding the pathogenesis of cerebral small vessel disease and the recent studies on blood pressure variability and circadian rhythm of blood pressure,this review discusses a series of scientific problems such as the effects of blood pressure variability and circadian rhythm of blood pressure on the occurrence and development of cerebral small vessel disease.

关 键 词：脑小血管病 高血压 血压变异性 血压节律 脑白质病变 

分 类 号：R743.3[医药卫生—神经病学与精神病学]