“重组人红细胞生成素制造工艺虚拟仿真实验”课程的建设与实践  

Development and implementation of the course entitled“Virtual Simulation Experiment of Recombinant Human Erythropoietin Manufacturing Process”

作　　者：冯佳 蒋建兰[1] 冯远航[1] 朱宏吉[1] 余林玲 赵广荣[1] 卢文玉[1] 史清洪[1] FENG Jia;JIANG Jianlan;FENG Yuanhang;ZHU Hongji;YU Linling;ZHAO Guangrong;LU Wenyu;SHI Qinghong(School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China)

机构地区：[1]天津大学化工学院,天津300072

出　　处：《生物工程学报》2024年第6期1950-1962,共13页Chinese Journal of Biotechnology

基　　金：第二批国家级一流本科课程(教高函[2023]7号);天津市虚拟仿真实验教学建设项目(津教政办[2019]69号);生物工程国家级一流专业建设(2019年);制药工程国家级一流专业建设(2020年)。

摘　　要：针对生物工程类专业制造工艺学习传统模式中存在的问题,本文阐述了“重组人红细胞生成素制造工艺虚拟仿真实验”课程的建设与实践过程。以重组人红细胞生成素药物为载体,将现代生物制造技术与三维信息技术高度融合。阐述了课程的教学理念、教学目标、教学内容、实施方式及实验方法和实验交互性操作步骤及考核标准。以学生为中心,创新实验方案设计、教学方法和评价体系,培养学生分析问题、解决复杂生物医药工程实际问题的能力,拓宽学生的思路和视野。Considering the issues present in traditional learning methods of manufacturing process for biotechnology majors, this paper presents the development and implementation process of the course entitled “Virtual Simulation Experiment of Recombinant Human Erythropoiesis Manufacturing Process”. The experiment combines modern biological manufacturing technology and three-dimensional information technology, with recombinant human erythropoiesis drug serving as the focal point. This paper elaborates on the teaching concepts, objectives, contents, implementation methods, experimental procedures, interactive steps, and assessment criteria used in the experiment. Through innovative experimental scheme design, teaching methodologies, and evaluation systems, this course aims to cultivate students’ analytical and problem-solving skills in the field of biopharmaceutical engineering, while also broadening students’ perspective and expanding their vision.

关 键 词：重组人红细胞生成素 虚拟仿真 生物工程类 教学改革 

分 类 号：G642.3[文化科学—高等教育学] Q81-4[文化科学—教育学]