外阴巨大血管肌纤维母细胞瘤磁共振成像误诊为脂肪肉瘤一例  

Giant Angiomyofibroblastoma of the Vulva Misdiagnosed as Liposarcoma on Magnetic Resonance Imaging:A Case Report

作　　者：马海燕 张芸中[2] 郑荣芳 王芙蓉[3] 张萌 郭钰珍[2] MA Hai-yan;ZHANG Yun-zhong;ZHENG Rong-fang;WANG Fu-rong;ZHANG Meng;GUO Yu-zhen(The Second Clinical Medical College of Lanzhou University,Lanzhou 730000,China;Department of Gynecology,The Second Hospital of Lanzhou University,Lanzhou 730000,China;Department of Pathology,The Second Hospital of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学第二临床医学院,730000 [2]兰州大学第二医院妇科 [3]兰州大学第二医院病理科

出　　处：《国际妇产科学杂志》2024年第3期263-266,共4页Journal of International Obstetrics and Gynecology

摘　　要：外阴血管肌纤维母细胞瘤(angiomyofibroblastoma,AMF)是一种育龄期女性罕见的良性肿瘤,起源于女性的外阴或阴道。脂肪肉瘤好发于围绝经期及绝经后女性的躯干、四肢等部位。报道1例外阴巨大AMF磁共振成像(magnetic resonance imaging,MRI)误诊为脂肪肉瘤的病例,该患者因发现外阴肿物3年,增大1年入院,术前MRI诊断为脂肪肉瘤,而术前活检诊断为AMF,行外阴肿物切除术+外阴成形术,术后病理检查诊断AMF,术后随访9个月未见复发。临床医生应加强疾病的鉴别诊断,通过结合术前组织病理学及其相关影像学检查可提高AMF的诊断准确率,为临床提供准确的手术指导信息。Vulvar angiomyofibroblastoma(AMF)is a rare benign tumor that occurs in women of childbearing age,originating from the vulva or vagina.Liposarcoma typically occurs in the trunk and limbs of perimenopausal and postmenopausal women.We report a case where a large vulvar AMF was initially misdiagnosed as liposarcoma by magnetic resonance imaging(MRI).The patient who was admitted to the hospital because of the discovery of a vulvar mass for 3 years that had enlarged over one year,was diagnosed with liposarcoma via preoperative MRI.However,a preoperative biopsy revealed AMF.The patient underwent excision of vulvar mass and vulvovaginoplasty.Postoperative pathology confirmed the AMF diagnosis,with no recurrence observed during the postoperative follow up for 9 months.Clinicians should enhance the differential diagnosis of such condition and improve the diagnostic accuracy of AMF by combining preoperative histopathology and related imaging examinations,providing accurate clinical information for surgical guidance.

关 键 词：血管肌瘤 肿瘤 肌组织 外阴 软组织肿瘤 脂肪肉瘤 磁共振成像 误诊 

分 类 号：R737.35[医药卫生—肿瘤] R445.2[医药卫生—临床医学]