基于隐结构模型和频繁项集的针刺治疗慢性前列腺炎辨证取穴规律  

Data Mining for Acupoint Selection Pattern in Acupuncture for Chronic Prostatitis Based on Latent Structure Model and Frequent Item Set

作　　者：胡创政 孙自学[2] 张宸铭[2] 樊立鹏 华众 付晓君 门波[2] HU Chuangzheng;SUN Zixue;ZHANG Chenming;FAN Lipeng;HUA Zhong;FU Xiaojun;MEN Bo(The Second Clinical Medical School,Henan University of Chinese Medicine,Zhengzhou 450046,China;Center of Reproductive Medicine,Henan Province Hospital of Traditional Chinese Medicine,Zhengzhou 450046,China)

机构地区：[1]河南中医药大学第二临床医学院,郑州450046 [2]河南省中医院生殖医学诊疗中心,郑州450046

出　　处：《世界中医药》2024年第8期1182-1187,共6页World Chinese Medicine

基　　金：国家自然科学基金面上项目(81974573);国家自然科学基金面上项目(82274536);河南省中医药科学研究专项课题(20-21ZY2052);河南省第二批中医青年人才培养项目。

摘　　要：目的:探讨针刺治疗慢性前列腺炎的辨证取穴规律,为临床治疗慢性前列腺炎提供帮助。方法:检索国家知识基础设施数据库(CNKI)、中文科技期刊数据库(CCD)等数据库中关于针刺辨证论治慢性前列腺炎的文献,构建包含症状、证型、穴位处方的慢性前列腺炎病历数据库,运用隐结构模型分析、频繁项集等方法,分析针刺治疗慢性前列腺炎的辨证取穴规律。结果:共纳入文献64篇,涉及穴位91个,症状248项。高频穴位如三阴交、中极等;高频症状包括舌体瘀点瘀斑、苔黄腻、滴白、尿急等;构建隐结构模型,得出慢性前列腺炎主要证型有湿热下注、肾阳不足等;挖掘出症状-穴位频繁项集、症状-证型-穴位频繁项集各4项。症状-穴位频繁项集如“尿急+滴白+阳痿+早泄+肾俞+足三里”,症状-证型-穴位频繁项集如“尿频+尿急+苔黄腻+滴白+舌体瘀点瘀斑+湿热瘀阻+三阴交+会阴”,提示治疗时可根据相应症状判定证型及选择对应穴位。结论:针刺治疗慢性前列腺炎多以三阴交、中极、关元等为主要穴位,穴位配伍依据临床情况辨证选穴,此可为临床治疗慢性前列腺炎提供参考。Objective:To mine the acupoint selection pattern in the acupuncture for chronic prostatitis and provide clues for clinical treatment of this disease.Methods:The articles about acupuncture for treating chronic prostatitis were retrieved from the China National Knowledge Infrastructure(CNKI) and Chinese Citation Database(CCD).A case library was built,containing symptoms,syndromes,and acupoint prescriptions.The latent structure model and frequent item set were employed to mine the acupoint selection pattern in the acupuncture for chronic prostatitis.Results:A total of 64 articles were included,involving 91 acupoints and 248 symptoms.The high-frequency acupoints included Sanyinjiao(SP6) and Zhongji(CV3),and the high-frequency symptoms included tongue petechiae and ecchymosis,yellow greasy tongue coating,prostatorrhoea,and urgent urination.A latent structure model was built,which indicated that the main syndromes of chronic prostatitis included dampness-heat pouring down and kidney yang deficiency.Four frequent item sets each of symptom-acupoint and symptom-syndrome-acupoint were mined out.A representative symptom-acupoint set was urgent urination+prostatorrhoea+impotence+premature ejaculation+Shenshu(BL23)+Zusanli(ST36).A representative symptom-syndrome-acupoint set was frequency of urination+urgent urination+yellow greasy tongue coating+prostatorrhoea+tongue petechiae and petechistasis+stasis and obstruction of dampness and heat+Sanyinjiao(SP6)+Huiyin(CV1).The results suggested that acupoints can be selected according to the syndrome identified based on corresponding symptoms.Conclusion:In the treatment of chronic prostatitis,Sanyinjiao(SP6),Zhongji(CV3),and Guanyuan(CV4) can be taken as the main acupoints for acupuncture.The acupoints can eb selected according to the syndromes.The findings of this study can provide a reference for the clinical treatment of chronic prostatitis.

关 键 词：隐结构模型 频繁项集 慢性前列腺炎 数据挖掘 辨证取穴规律 针刺 穴位 APRIORI算法 

分 类 号：R245[医药卫生—针灸推拿学]