Clinical characteristics of postoperative necrotizing enterocolitis in patients with congenital jejunoileal atresia and its risk factors  

作　　者：Xiaofeng Xiong Wei Lu Fuzhong Xing Yuan Cai Jixin Yang Yuhang Yuan Jiexiong Feng Xuyong Chen 

机构地区：[1]Department of Pediatric Surgery,Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology,Wuhan,Hubei,China [2]Department of Neonate Surgery,Wuhan Children's Hospital,Huazhong University of Science and Technology,Wuhan,Hubei,China [3]Department of Pediatric Surgery,The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China

出　　处：《World Journal of Pediatric Surgery》2024年第1期42-46,共5页世界小儿外科杂志（英文）

基　　金：funding from the National Natural Science Foundation of China(82371720);Clinical Research Pilot Project of Tongji Hospital(2019YBKY026);the Provincial Key Research and Development Program(2020BCB008)。

摘　　要：Objective To review postoperative necrotizing enterocolitis(NEC)in patients with jejunoileal atresia(JIA)and to explore the potential risk factors related to the concurrence ofNEC.Methods Patients diagnosed with JIA who received surgical treatment from January 2016 to June 2021 were enrolled.Demographics,viral infection of the fetus,transfusion within 48 hours before NEC,sepsis before JIA repair,pathological and anatomical classification of JIA,combined malformation,occurrence time of NEC after the operation,treatment,and prognosis of patients were analyzed.Patients were divided into NEC group and non-NEC group,and all patients were followed up for 3-6 months to observe for complications.Results A total of 180 patients with JIA were included,of whom 12 were diagnosed with NEC after surgery and 1 patient with NEC died during follow-up.The average age,birth weight,gestational age,proportion of premature infants,proportion of preoperative infections,and pathological classification of JIA did not significantly differ between the two groups.The probability of patients with proximal jejunal atresia(PJA)in the NEC group(58.3%)was higher than that in the non-NEC group(22.6%)(p=0.011),and patients with PJA had longer parenteral nutrition time than patients without PJA(26.64±9.21 days vs 15.11±6.58 days,p<0.001).Conclusion PJA was more likely to be associated with concurrent NEC after surgery,which is a highly NEC-related risk factor inherent in JIA.

关 键 词：PATIENTS POSTOPERATIVE TRANSFUSION 

分 类 号：R574[医药卫生—消化系统]