以微生物群为导向的食物干预在营养不良患儿中的研究进展  

Progress of microbiota-directed food intervention for malnourished children

作　　者：赖乾坤[1] 王钰莹 郭敬民[1] Qiankun Lai;Yuying Wang;Jingmin Guo(Department of Children Healthcare,Fujian Maternity and Child Health Hospital(College of Clinical Medicine for Obstetrics&Gynecology and Pediatrics,Fujian Medical University),Fuzhou 350001,China)

机构地区：[1]福建省妇幼保健院(福建医科大学妇儿临床医学院)儿保科,福州350001

出　　处：《国际儿科学杂志》2024年第4期245-249,共5页International Journal of Pediatrics

摘　　要：保持肠道微生物的稳态对维持人体健康至关重要。人体肠道微生物的演变参与诸多的生理功能,生命早期肠道微生物群就开始出现变化。婴幼儿的营养不良发病率居高不下,尤其在中低收入国家。越来越多研究证实,肠道微生物群的发育不成熟及其代谢物异常与营养不良有关。营养饮食是影响肠道微生物群的最主要因素,已有研究开始致力于评估以微生物群为导向的食物干预,在改善婴幼儿营养不良中的潜在治疗价值。因此,该文总结了该领域的最新进展,以期寻找新的婴幼儿营养不良治疗手段。Maintaining the homeostasis of gut microbes is essential for the maintenance of human health.The evolution of the human gut microbiota is involved in many physiological functions.Besides,changes in gut flora can be traced back to early life.The prevalence of malnutrition in infants and young children is persistently high,especially in low-and middle-income countries.More and more researches have confirmed that the immature development of intestinal microbiota and abnormal metabolites are related to malnutrition.Due to nutritional diet is the most important factor affecting the microbiota,studies have begun to assess the therapeutic potential of microbiota oriented food interventions in improving infant and young child malnutrition.Therefore,this review summarizes the latest advances in the field and recommend further progress towards finding new treatments for the malnutrition of infant and young child.

关 键 词：微生物群 营养不良 食物干预 婴幼儿 

分 类 号：R723.11[医药卫生—儿科]