解密baccatin Ⅲ生物合成途径,奠定紫衫烷可持续获取途径  

Uncovering the baccatin III biosynthetic pathway for sustainable taxoid supply

作　　者：谭仁祥 陈晓亚 Ren Xiang Tan;Xiao-Ya Chen(State Key Laboratory of Pharmaceutical Biotechnology,Institute of Functional Biomolecules,School of Life Sciences,Nanjing University,Nanjing 210023,China;State Key Laboratory of Plant Molecular Genetics,CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Shanghai 200032,China)

机构地区：[1]State Key Laboratory of Pharmaceutical Biotechnology,Institute of Functional Biomolecules,School of Life Sciences,Nanjing University,Nanjing 210023,China [2]State Key Laboratory of Plant Molecular Genetics,CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Shanghai 200032,China

出　　处：《Science Bulletin》2024年第9期1182-1184,共3页科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China (81991524, 32388201);Yunnan Revitalization Talent Support Program Project (202305AT350001)。

摘　　要：The characterization and reconstitution of Taxus enzymes leading to taxoids (diterpenoids with the taxane skeleton seen in the taxol molecule)[1–5] are exciting and may tempt researchers to update the episode about taxol that has been, and will be, prescribed to combat diverse cancers.

关 键 词：PRESCRIBED SKELETON baccatin 

分 类 号：TQ460.1[化学工程—制药化工]