内侧杏仁核的神经调节素1信号通路调控青春期社会隔离导致的自闭样行为  

Medial amygdala NRG1 signaling mediates adolescent social isolation-induced autistic-like behaviors

作　　者：林连虹 吴倩云 曾恺 陈梓瑜 王梓萍 李伟民 张斌 高天明 刘吉红 Lian-Hong Lin;Qian-Yun Wu;Kai Zeng;Zi-Yu Chen;Zi-Ping Wang;Wei-Min Li;Bin Zhang;Tian-Ming Gao;Ji-Hong Liu(Department of Psychiatry,Institute of Brain Disease,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence,Southern Medical University,Guangzhou 510515,China)

机构地区：[1]Department of Psychiatry,Institute of Brain Disease,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China [2]Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence,Southern Medical University,Guangzhou 510515,China

出　　处：《Science Bulletin》2024年第10期1375-1379,共5页科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China(82071488 and 82271525);the Natural Science Foundation of Guangdong Province(2023A1515010456 and 2021A1515012181).

摘　　要：Autistic spectrum disorder(ASD),characterized by impairments in social interaction and repetitive behaviors,is a complex neurodevelopmental brain disorder that is reportedly increasing in prevalence globally[1].It is widely accepted that genetic and environmental factors alone or in combination cause ASD[2].

关 键 词：社会隔离 IMPAIRMENT PREVALENCE 

分 类 号：Q421[生物学—神经生物学]