术中冰冻检查在乳腺癌肿瘤组织级别和肿物组织学大小中的诊断价值  

Diagnostic Value of Intraoperative Frozen Section in Tumor Grade and Tumor Histological Size of Breast Cancer

作　　者：钟全钰 ZHONG Quan-yu(Department of Pathology,Xinfeng County People's Hospital,Xinfeng 341600,Jiangxi,China)

机构地区：[1]信丰县人民医院病理科,江西信丰341600

出　　处：《医学信息》2024年第12期144-147,共4页Journal of Medical Information

摘　　要：目的研究术中冰冻检查在不同乳腺癌肿瘤组织级别和肿物组织学大小中的诊断价值。方法以2021年1月-2023年3月信丰县人民医院行手术治疗的62例乳腺癌患者为研究对象,依次开展术中冰冻切片检查与常规石蜡切片检查,比较术中冰冻检查与常规石蜡切片检查对乳腺癌不同病理类型的诊断结果,以石蜡切片诊断结果为金标准,分析术中冰冻检查对不同肿瘤组织级别及肿物组织学大小的诊断准确率。结果术中冰冻检查与常规石蜡切片检查对乳腺癌不同病理类型的诊断结果比较,差异无统计学意义(P>0.05)。以石蜡切片诊断结果为金标准,术中冰冻检查对Ⅰ级、Ⅱ级、Ⅲ级乳腺癌诊断准确率分别为86.96%(20/23)、92.86%(26/28)、100.00%(11/11)。以石蜡切片诊断结果为金标准,术中冰冻检查对<3.5 cm、≥3.5 cm大小组织的诊断准确率分别为89.74%(35/39)、95.65%(22/23)。结论术中冰冻检查在乳腺癌病理检查中具有较高诊断价值,其诊断结果与临床金标准较为一致,在不同肿瘤组织级别及肿物组织学大小中均具有较高诊断准确率。Objective To study the diagnostic value of intraoperative frozen section in different breast cancer tissue grade and tumor histological size.Methods From January 2021 to March 2023,62 patients with breast cancer who underwent surgical treatment in Xinfeng County People's Hospital were selected as the research objects.Intraoperative frozen section examination and conventional paraffin section examination were carried out in turn.The diagnostic results of different pathological types of breast cancer by intraoperative frozen section examination and conventional paraffin section examination were compared.The diagnostic accuracy of intraoperative frozen section examination for different tumor tissue grades and tumor histological sizes was analyzed with paraffin section diagnosis results as the gold standard.Results There was no significant difference in the diagnosis of different pathological types of breast cancer between intraoperative frozen examination and conventional paraffin section examination(P>0.05).With the diagnostic results of paraffin sections as the gold standard,the diagnostic accuracy of intraoperative frozen section for gradeⅠ,gradeⅡand gradeⅢbreast cancer was 86.96%(20/23),92.86%(26/28)and 100.00%(11/11),respectively.With the diagnostic results of paraffin sections as the gold standard,the diagnostic accuracy of intraoperative frozen section for tissues<3.5 cm and≥3.5 cm was 89.74%(35/39)and 95.65%(22/23),respectively.Conclusion Intraoperative frozen examination has high diagnostic value in pathological examination of breast cancer,and its diagnostic results are consistent with the clinical gold standard.It has high diagnostic accuracy in different tumor tissue grades and tumor histological sizes.

关 键 词：乳腺癌 术中冰冻检查 肿瘤组织分级 石蜡切片 

分 类 号：R737.9[医药卫生—肿瘤]