单中心慢性胰腺炎的临床特征和治疗模式10年变迁  

Clinical characteristics and treatment mode changes of chronic pancreatitis:a 10‐year single center study

作　　者：魏婉珍 段万星 赵锦鹏 武帅 钱伟琨 仵正[1] 杨雪 王铮[1] Wei Wanzhen;Duan Wanxing;Zhao Jinpeng;Wu Shuai;Qian Weikun;Wu Zheng;Yang Xue;Wang Zheng(Department of Hepatobiliary Surgery,Pancreatic Disease Center,the First Affiliated Hospital of Xi′an Jiaotong University,Xi′an 710061,China)

机构地区：[1]西安交通大学第一附属医院肝胆外科胰腺疾病诊疗中心,西安710061

出　　处：《中华消化外科杂志》2024年第5期726-732,共7页Chinese Journal of Digestive Surgery

基　　金：国家自然科学基金(82072702、82372859);陕西省自然科学基金(2023⁃JC⁃ZD⁃54);中央高校基本科研业务费专项资金(xtr052022008);陕西省创新能力支持计划科技创新团队项目(2022TD⁃43);陕西省“高层次人才特殊支持计划”科技创新领军人才项目(KSJRC202204)。

摘　　要：目的探讨慢性胰腺炎(CP)的临床特征和治疗模式变迁。方法采用回顾性描述性研究方法。收集2013年1月至2022年12月西安交通大学第一附属医院收治的805例CP患者的临床资料;男575例,女230例;年龄为52(10~87)岁。观察指标:(1)人口学特征。(2)收治科室分布、住院及治疗情况。正态分布的计量资料以x±s表示,偏态分布的计量资料以M(范围)表示。计数资料以绝对数和百分比表示。期望频数是否符合经验分布采用拟合优度χ^(2)检验。结果(1)人口学特征。805例患者中,依据主要诊断标准和次要诊断标准确诊CP分别为435例和370例,首次就诊年龄为52(10~87)岁,其中0~10岁、11~20岁、21~30岁、31~40岁、41~50岁、51~60岁、61~70岁、71~80岁、81~90岁的男性和女性患者分别为1和0例、16和14例、45和26例、82和30例、122和39例、157和51例、119和46例、31和21例、2和3例。2013年,2014年,2015年,2016年,2017年,2018年,2019年,2020年,2021年,2022年收治的0~14岁、15~34岁、35~64岁和≥65岁患者分别为0、6、28和9例,1、21、34和10例,1、8、38和7例,0、7、52和10例,0、11、35和9例,1、15、72和23例,0、9、55和11例,2、19、58和16例,0、20、79和18例,0、25、73和22例。805例患者中,来自陕西省、甘肃省和其他地区分别为702、48和55例;汉族和回族患者分别为802和3例;已婚、未婚、离婚和丧偶患者分别为732、64、7和2例;病例资料中有血型记录为682例,其中A型、B型、AB型和O型占比分别为26.10%(178/682)、34.46%(235/682)、9.97%(68/682)和29.47%(201/682),以2022年陕西省人口血型分布特征(A型28.43%、B型30.50%、AB型9.83%和O型30.50%)为期望频数,两者比较,差异无统计学意义(χ^(2)=0.50,P>0.05)。(2)收治科室分布、住院及治疗情况。805例患者中,肝胆外科,消化内科和其他科室(老年外科、感染科、普通外科等)收治入院分别为594、121和90例,收治患者例次分别为771、121和94例次,�Objective To investigate the clinical characteristics and treatment mode changes of chronic pancreatitis(CP).Methods The retrospective and descriptive study was conducted.The clinical data of 805 patients with CP who were admitted to the First Affiliated Hospital of Xi′an Jiaotong University from January 2013 to December 2022 were collected.There were 575 males and 230 females,aged 52(range,10−87)years.Observation indicators:(1)demographic characteristics;(2)distribution of admission departments,hospitalization and treatment status.Measurement data with normal distribution were represented as Mean±SD,and measurement data with skewed distribution were represented as M(range).Count data were expressed as absolute numbers and percentages.The chi‐square goodness‐of‐fit test was used for consistent between expected frequency and empirical distribution.Results(1)Demographic characteristics.Of the 805 patients,there were 435 cases and 370 cases diagnosed as CP according to the primary and secondary diagnostic criteria,respectively,and the age of initial presentation of 805 patients was 52(range,10−87)years.Among male and female patients,there was 1 and 0 case in the age group of 0−10 years,there were 16 and 14 cases in 11−20 years,45 and 26 cases in 21−30 years,82 and 30 cases in 31−40 years,122 and 39 cases in 41−50 years,157 and 51 cases in 51−60 years,119 and 46 cases in 61−70 years,31 and 21 cases in 71−80 years,2 and 3 cases in 81−90 years,respectively.Patients aged 0−14,15−34,35−64,and≥65 years were 0,6,28,and 9 for 2013,1,21,34,and 10 for 2014,1,8,38,and 7 for 2015,0,7,52,and 10 for 2016,0,11,35 and 9 for 2017,1,15,72 and 23 for 2018,0,9,55 and 11 for 2019,2,19,58 and 16 for 2020,0,20,79 and 18 for 2021,0,25,73 and 22 for 2022,respectively.Of the 805 patients,cases from Shaanxi Province,Gansu Province and other regions were 702,48 and 55,respectively.There are 802 Han and 3 Hui patients,respectively,and the married,unmarried,divorced,and widowed patients were 732,64,7,and 2,

关 键 词：胰腺炎 慢性 经内镜逆行胆胰管成像 胰腺体外冲击波碎石 手术治疗 

分 类 号：R576[医药卫生—消化系统]