一种合成4-亚苄基-3-甲基-1-苯基吡唑啉酮的新方法  

A New Method for Synthesis of 4-Benzylidene-3-methyl-1-phenylpyrazolone

作　　者：赵林权 刘敏 杨艳春 刘璐 宋祥家 ZHAO Linquan;LIU Min;YANG Yanchun;LIU Liu;SONG Xiangjia(College of Chemical Engineering,North China University of Science and Technology,Tangshan 063009,China)

机构地区：[1]华北理工大学化学工程学院,河北唐山063009

出　　处：《化工技术与开发》2024年第6期15-17,40,共4页Technology & Development of Chemical Industry

摘　　要：4-亚苄基-3-甲基-1-苯基吡唑啉酮是一种重要的合成子,合成4-亚苄基-3-甲基-1-苯基吡唑啉酮的方法较多,但反应条件较为苛刻。本文用苯并噻唑亚胺与吡唑酮进行反应,合成了4-亚苄基-3-甲基-1-苯基吡唑啉酮,收率高达96%,并进行了普适性研究,均能以较好的收率得到目标产物。As an important synthon,there were many methods to synthesize 4-benzylidene-3-methyl-1-phenyl pyrazolone,but the conditions were harsh.In this paper,through the reaction of benzothiazolimines with pyrazolone,4-benzylidene-3-methyl-1-phenylpyrazolone was synthesized with 96% yield.The generalization studies were carried out,all of which gave the target products in good yields.

关 键 词：4-亚苄基-3-甲基-1-苯基吡唑啉酮 苯并噻唑亚胺 吡唑酮 

分 类 号：O623.52[理学—有机化学]