脂质标志物与颈动脉粥样硬化  

Lipid markers and carotid atherosclerosis

作　　者：景文君 刘华坤[2] 郭智鹏 Jing Wenjun;Liu Huakun;Guo Zhipeng(Jining Medical College,Jining 272067,China;Department of Neurology,Jining First People's Hospital,Jining 272011,China)

机构地区：[1]济宁医学院,济宁272067 [2]济宁市第一人民医院神经内科,272011

出　　处：《国际脑血管病杂志》2024年第2期140-144,共5页International Journal of Cerebrovascular Diseases

基　　金：山东省医药卫生科技项目(202303070266)。

摘　　要：颈动脉粥样硬化(carotid atherosclerosis,CAS)是一种常见、复杂且严重的颈动脉病变,同时也是缺血性卒中的重要危险因素。近年来的研究显示,CAS的患病率呈上升趋势,对卒中的一级和二级预防造成很大压力。脂质水平升高与CAS严重程度及进展速度密切相关,这为CAS的早期预测、诊断和治疗提供了有力支持。文章对各种脂质标志物与CAS的关系进行了综述。Carotid atherosclerosis(CAS)is a common,complex and serious carotid artery disease,and also an important risk factor for ischemic stroke.In recent years,researches have shown that the incidence of CAS is on the rise,putting great pressure on the primary and secondary prevention of stroke.The elevated lipid levels are closely associated with the severity and progression of CAS,and this provides strong support for early prediction,diagnosis,and treatment of CAS.This article reviews the relationship between various lipid biomarkers and CAS.

关 键 词：颈动脉疾病 动脉粥样硬化 胆固醇 HDL 胆固醇 LDL 脂蛋白 HDL 脂蛋白(a) 载脂蛋白类 生物标志物 

分 类 号：R743[医药卫生—神经病学与精神病学]