耳甲腔毛母细胞瘤1例并文献复习  

A case of trichoblastoma of the auricular cavity and review of the literature

作　　者：李雪雪 卫旭东 李淑娟[2] 王倩茹 潘鑫 LI Xuexue;WEI Xudong;LI Shujuan;WANG Qianru;PAN Xin(First Clinical College of Medicine,Lanzhou University,Lanzhou,730000,China;Department of Otolaryngology,Head and Neck Surgery,Gansu Provincial People's Hospital;Gansu University of Traditional Chinese Medicine)

机构地区：[1]兰州大学第一临床医学院,兰州730000 [2]甘肃省人民医院耳鼻咽喉头颈外科 [3]甘肃中医药大学

出　　处：《临床耳鼻咽喉头颈外科杂志》2024年第5期448-452,共5页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：毛母细胞瘤(trichoblastoma,TB)是一种罕见的毛发生殖细胞皮肤附件肿瘤,罕见的皮肤滤泡肿瘤,分化于毛胚上皮,常被视为良性皮肤肿瘤,但局限性差且具有局部浸润性生长模式。TB好发于头部和颈部区域,尤其是面部,临床表现为生长缓慢、边界清晰及隆起的结节。TB常规以手术治疗为主,由于目前缺乏普遍接受的治疗指南或方案,术后复发率高,为临床治愈增加了一定的难度。本研究报道1例65岁女性患者,发现右侧外耳道口及耳甲腔肿物并反复破溃流脓,最初误诊为外耳道炎,以常规抗感染治疗,症状未缓解并逐渐加重后来我院就诊。该病例所展现的病症极为罕见,因此,及时且准确的诊断与治疗对此类疫病的诊疗和预后至关重要。Trichoblastoma(TB)is a rare germ cell skin adnexal tumor of the hair,and it is a rare follicular tumor of the skin that differentiates from the hair germ epithelium and is often regarded as a benign skin tumorHowever,it is poorly confined and has a local infiltrative growth pattern.tb occurs in the head and neck region,especially in the face,and presents clinically as a slow growing,well-defined and elevated nodule.TB is routinely treated surgically.Due to the lack of universally accepted treatment guidelines or protocols,the recurrence rate after surgery is high,which makes clinical cure more difficult.In this study,a 65-year-old female patient was found to have a swelling with recurrent rupture and pus flow from the right external auditory canal opening and the auricular cavity.After initial misdiagnosis as otitis externa,she was treated with conventional anti-infective therapy,but her symptoms did not resolve and gradually worsened before coming to our hospital.The condition presented in this case is relativelyrare,therepre,timely and accurate diagnosis and treatment are crucial for prognosis improvement of such diseases.

关 键 词：毛母细胞瘤 毛源性肿瘤 耳甲腔良性肿瘤 诊断 治疗 

分 类 号：R739.61[医药卫生—肿瘤]