血小板纤维蛋白在下颌阻生第三磨牙拔除后邻牙远中骨缺损修复中应用  

Effect of Platelet-rich Fibrin Membrane in the Repair of Distal Bone Defect of the Third Molar Extraction

作　　者：闫景 高金波[1] Yan Jing;Gao Jinbo(The Third Central Hospital of Tianjin,Tianjin,300170,China)

机构地区：[1]天津市第三中心医院,天津300170

出　　处：《黑龙江医学》2024年第11期1300-1304,共5页Heilongjiang Medical Journal

摘　　要：目的:系统评价血小板纤维蛋白(PRF)膜应用于下颌阻生第三磨牙拔除后第二磨牙远中骨质缺损修复的疗效。方法:全面检索数据库中PRF膜用于拔除下颌阻生第三磨牙的临床随机对照试验,检索时间为自建库至2022年10月,采用RevMan5.3软件进行数据分析。结果:共9篇文章纳入分析研究。Meta分析结果显示:第三磨牙拔除后放置PRF膜能明显降低第二磨牙远中牙周袋深度(PD)[SMD=-1.22,95%CI(-1.84,-0.60),P=0.0001]、拔牙区骨高度(ABH)[SMD=-1.56,95%CI(-2.54,-0.59),P=0.002]及骨密度(BMD)[SMD=0.81,95%CI(0.46,1.16),P<0.00001]明显增加;但第二磨牙远中附着水平(CAL)及牙龈退缩程度(GR)无明显改变。结论:下颌阻生第三磨牙拔除后同期植入PRF膜有利于促进第二磨牙远中骨缺损的愈合。Objective:To evaluate the effect of PRF membrane in the repair of distal bone defect of second molar after impacted third molar tooth extraction.Methods:The clinical randomized controlled trials of PRF membrane used in extraction of impacted mandibular third molars were comprehensively searched from database until October 2022,and the data were analyzed by Revman 5.3 software.Results:9 papers were included in the meta-analysis.The results of meta analysis showed that the placement of PRF membrane could significantly reduce the depth of distal periodontal pocket of the second molar[SMD=-1.22,95%CI(-1.84,-0.60),P=0.0001],increase the bone density[SMD=-1.56,95%CI(-2.54,-0.59),P=0.002]and the bone height of extraction area[SMD=0.81,95%CI(0.46,1.16),P<0.00001].However,there was no significant change in the distal attachment level of the second molar and the degree of gingival recession.Conclusion:PRF membrane can significantly promote the distal bone repair of the second molar than the third molar tooth extraction alone.

关 键 词：阻生齿拔除 血小板纤维蛋白 骨缺损 Meta分析 

分 类 号：R782[医药卫生—口腔医学]