儿童胸腺淋巴上皮瘤样癌的CT表现及临床特征并文献复习  

CT manifestations and clinical features of thymic lymphoepithelioma-like carcinoma in children and literature review

作　　者：杨利新[1] 胡迪[1] 韩忠龙[1] 杨双风 彭芸[1] YANG Lixin;HU Di;HAN Zhonglong;YANG Shuangfeng;PENG Yun(Imaging Center,Beijing Children's Hospital,Capital Medical University,Beijing 100045,China)

机构地区：[1]首都医科大学附属北京儿童医院影像中心,北京100045

出　　处：《实用放射学杂志》2024年第5期789-792,共4页Journal of Practical Radiology

基　　金：北京市医院管理中心“登峰”计划专项项目(DFL20221002)。

摘　　要：目的探讨儿童胸腺淋巴上皮瘤样癌(LELC)的CT表现及临床特征。方法回顾性分析5例经病理证实的LELC患儿的CT表现及临床特征,并复习相关文献。结果5例患儿均可见前中纵隔巨大软组织肿块(3例可见少许点状钙化),呈分叶状,增强后肿瘤呈明显不均匀强化,并可见囊变、坏死,肿物压迫、包绕并侵犯周围结构。文献检索LELC患儿共21例。结论儿童胸腺LELC多好发于10~16岁青春期男孩,患者多以肿瘤压迫或侵犯周围结构的症状就诊,临床分期晚,预后差。CT增强可以准确显示病灶及邻近结构侵犯情况,指导临床分期及治疗。Objective To investigate the CT manifestations and clinical features of thymic lymphoepithelioma-like carcinoma(LELC)in children.Methods The CT findings and clinical features of 5 children with LELC confirmed by pathology were analyzed retrospectively,and relevant literatures were reviewed.Results All the five children showed a large soft tissue mass(a few punctuate calcifications in 3 cases)in the anterior and middle mediastinum,which was lobulated.After enhancement,the tumor showed significant heterogeneous enhancement with cystic,necrosis,compressing,surrounding and invading adjacent structures.Twenty-one children with LELC were searched in literatures.Conclusion Thymic LELC in children usually occurs in adolescent boys aged 10-16 years.Those children usually go to the doctor with symptoms of tumor compression or invasion of adjacent structures.LELC shows advanced clinical stage with poor prognosis.CT enhancement can accurately display the lesion and invasion of adjacent structures,and guide clinical staging and treatment.

关 键 词：儿童 胸腺 淋巴上皮瘤样癌 计算机体层成像 

分 类 号：R736.3[医药卫生—肿瘤] R814.42[医药卫生—临床医学]