首发难治性精神分裂症患者的头颅CT扫描及脑部形态改变特征分析  

Head CT scanning and morphological changes of brain in patients with first refractory schizophrenia

作　　者：卢童新 李玉美 吴东 汪爱妩 赵勇 LU Tongxin;LI Yumei;WU Dong;WANG Aiwu;ZHAO Yong(Department of Medical Technology,the Third People's Hospital of Yichun City,Yichun,Jiangxi,336000,China)

机构地区：[1]宜春市第三人民医院医技科,江西宜春336000

出　　处：《当代医学》2024年第7期73-77,共5页Contemporary Medicine

摘　　要：目的探究首发难治性精神分裂症患者的头颅CT扫描及脑部形态改变特征。方法选取2019年1月至2021年12月宜春市第三人民医院接诊的90例首发难治性精神分裂症患者作为研究组,另选取同期接诊的90例普通精神分裂症患者作为对照组,均进行头颅CT检查,比较两组检查结果及颅脑CT影像改变。结果研究组皮质异常、侧脑室异常、小脑萎缩、透明隔腔检出率高于对照组,差异有统计学意义(P<0.05)。研究组前纵裂池最大宽度、额叶额上沟最宽距离、外侧裂垂直部最宽距离(右)、外侧裂垂直部最宽距离(左)、外侧裂水平部最宽距离(左)、外侧裂水平部最宽距离(右)长于对照组,差异有统计学意义(P<0.05);研究组侧脑室占脑室指数(VBR)、前角指数(FHI)高于对照组,室中央指数(CMI)、前额叶萎缩指数(PFAI)低于对照组,差异有统计学意义(P<0.05);研究组侧脑室前角间最大宽度短于对照组,侧脑室前角间最小宽度、第三脑室体部最大宽度、侧脑室颞角最大宽度(左)、侧脑室颞角最大宽度(右)均长于对照组,差异有统计学意义(P<0.05);研究组左侧中央旁小叶、左侧额极、右侧额上回、左侧额上回均短于对照组,差异有统计学意义(P<0.05)。结论采用颅脑CT检查首发难治性精神分裂症患者,可明确患者脑部形态改变特征,判断脑损害及脑萎缩程度,以指导后续治疗,具有较高应用价值。Objective To explore the head CT scanning and morphological changes of brain in patients with first refractory schizophrenia.Methods 90 cases of first refractory schizophrenia patients admitted to the Third People's Hospital of Yichun City from January 2019 to December 2021 were selected as the study group,90 cases of schizophrenia patients admitted during the same period were selected as the control group,all of them underwent head CT examination was performed in two groups,and the examination effect and head CT image changes were compared between the two groups.Results The detection rates of cortical abnormalities,lateral ventricular abnormalities,cerebellar atrophy,and transparent septum in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The maximum width of the anterior longitudinal fissure pool,the widest distance of the frontal lobe hook,the widest distance from the vertical part of the lateral fissure(right),the widest distance from the vertical part of the lateral fissure(left),the widest distance from the horizontal part of the lateral fissure(left),and the widest distance of the horizontal part of the lateral fissure(right)in the study group were longer than those in the control group,and the differences were statistically significant(P<0.05);the ventricle to brain ratio(VBR)and frontal horns index(FHI)of the lateral ventricle were higher than those in the control group,while the cella media index(CMI)and pre-frontal atrophy index(PFAI)in the study group were lower than those in the control group,the differences were statistically significant(P<0.05);the maximum width between the anterior ventricles in the study group was shorter than that in the control group,and the minimum width between the anterior ventricles of the study group,the maximum width of the body part of the third ventricle,the maximum width of the temporal Angle of the lateral ventricle(left)and the maximum width of the temporal Angle of the lateral ventricle(right)we

关 键 词：首发难治性精神分裂症 头颅CT检查 脑部形态特征改变 相关性分析 

分 类 号：R749.3[医药卫生—神经病学与精神病学]