重视对早发性结直肠癌的认识  

Emphasis on awareness of early-onset colorectal cancer

作　　者：胡烨婷[1] 肖乾 丁克峰[1,2] 郑树 Hu Yeting;Xiao Qian;Ding Kefeng;Zheng Shu(Department of Colorectal Surgery,the Second Affiliated Hospital,Zhejiang University School of Medicine、Key Laboratory of Cancer Prevention and Intervention,Ministry of Education、Zhejiang Provincial Clinical Medical Research Center for Malignant Tumors,Hangzhou 310009,China;Center for Medical Research and Innovation in Digestive System Tumors,Ministry of Education,Hangzhou 310058,China)

机构地区：[1]浙江大学医学院附属第二医院大肠外科、恶性肿瘤预警与干预教育部重点实验室、浙江省恶性肿瘤临床医学研究中心,杭州310009 [2]消化系统医药基础研究创新中心(教育部),杭州310058

出　　处：《中华胃肠外科杂志》2024年第5期430-435,共6页Chinese Journal of Gastrointestinal Surgery

基　　金：国家重点研发计划(2017YFC0908200);浙江省重点研发计划项目“领雁”计划(2023C03049)。

摘　　要：50岁以下人群中早发性结直肠癌(EOCRC)的发病率和死亡率呈上升趋势。尽管传统流行病学研究已经做了较为深入的研究,筛选出与EOCRC相关的环境因素,但对其病因、机制及治疗的认识还远远不够。因此,本文总结了EOCRC的当前研究进展,特别关注流行病学、筛查现状、临床症状和预后情况,为包括精准筛查在内的二级预防提供新依据,为改善EOCRC治疗提供诊疗新思路。The incidence and mortality rates of early-onset colorectal cancer(EOCRC)among people under 50 years old are showing an upward trend.Although traditional epidemiological studies have conducted relatively deep research and screened out environmental factors related to EOCRC,our understanding of the causes,mechanisms,and treatment of this disease is still far from sufficient.In this review,we clarify the current progress of EOCRC,with a particular focus on epidemiology,screening status,clinical symptoms,and prognosis.This provides new evidence for secondary prevention,including precision screening,and offers new ideas for improving the diagnosis and treatment of EOCRC.

关 键 词：结直肠肿瘤 早发性 流行病学 筛查 临床特征 

分 类 号：R735.34[医药卫生—肿瘤]