不同生命阶段微塑料暴露的神经毒性研究进展  

Research Progress on Neurotoxicity of Microplastics Exposure in Different Stages of Life

作　　者：耿燕陪 李康 林本成 吕鹏[1] 袭著革 Geng Yanpei;Li Kang;Lin Bencheng;Lu Peng;Xi Zhuge(School of Public Health,Binzhou Medical University,Yantai 264000,China;Institute of Environmental and Operational Medicine,Academy of Military Medicine,Academy of Military Sciences,Tianjin 300050,China)

机构地区：[1]滨州医学院公共卫生学院,烟台264000 [2]军事科学院军事医学研究院环境医学与作业医学研究所,天津300050

出　　处：《生态毒理学报》2024年第3期180-191,共12页Asian Journal of Ecotoxicology

基　　金：国家自然科学基金面上项目(82073507)。

摘　　要：微塑料作为一种新型环境污染物,其对人体健康的影响日益受到关注。现有研究表明,微塑料能够通过多种途径进入人体,并对神经系统产生毒性作用。本文综述了微塑料的种类、来源及暴露途径,重点阐述了微塑料在人体不同生命阶段(胎儿期、婴幼儿期、成人期、老年期)暴露的神经毒性效应及其可能机制,为进一步评估其健康风险和采取有效的防控对策提供参考依据。As a new type of environmental pollutant,microplastics have been increasingly receiving attention for their impact on human health.Current research indicates that microplastics can enter the human body through v arious routes and exert neurotoxic effects.This article reviews the types,sources,and exposure pathways of m icroplastics,with a focus on the neurotoxic effects and potential mechanisms of microplastic exposure at different life stages in humans(fetal,infant,adult,and elderly).This review provides a comprehensive understanding of the neurotoxicity of microplastic exposure and its implications for human health risk assessment and effective p revention strategies.

关 键 词：微塑料 神经毒性 神经发育 神经退行性疾病 氧化应激 

分 类 号：X171.5[环境科学与工程—环境科学]