基于CiteSpace和VOSviewer可视化软件对饮食限制调控炎症的研究现状与热点分析  

Research status and hotspot analysis of dietary restriction regulating inflammation based on CiteSpace and VOSviewer visualization software

作　　者：童晓琼[1] 吴历[1] 张莉[1] 袁斌[2] 李芋均[3] 白大章 蒋国会[1] Tong Xiaoqiong;Wu Li;Zhang Li;Yuan Bin;Li Yujun;Bai Dazhang;Jiang Guohui(Department of Neurology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China;Institute of Materia Medica,School of Pharmacy,North Sichuan Medical College,Nanchong 637000,China;Department of Foreign Language,North Sichuan Medical College,Nanchong 637000,China)

机构地区：[1]川北医学院附属医院神经内科,南充637000 [2]川北医学院药物研究所,南充637000 [3]川北医学院外语系,南充637000

出　　处：《中国医学装备》2024年第6期149-156,共8页China Medical Equipment

基　　金：四川省自然科学基金面上项目(2023NSFSC0709)。

摘　　要：目的:基于CiteSpace和VOSviewer可视化软件对饮食限制(DR)调控炎症文献进行定量可视化分析,探索DR调控炎症领域的研究热点和趋势。方法:检索2010年1月1日至2022年9月29日Web of Science核心数据库中收录的DR调控炎症相关文献共1678篇,经筛查最终获得1344篇,使用CiteSpace和VOSviewer可视化软件对检索到的文献数据进行年发文量、国家、机构、作者、被引频次和关键词的定量和可视化分析。结果:最终获得的1344篇文献年发文量总体呈上升趋势,文献最高被引频次为1676次,美国(481篇)是出产文献数量最多的国家,中国(181篇)位居第二。DR调控炎症领域研究热点集中在热量限制(CR)、生酮饮食、衰老、代谢性疾病、脂肪组织及肠道菌群等方面。结论:DR调控炎症愈来愈受到国际和国内研究者青睐,未来研究热点可能是CR模拟物(CRM)、肠道菌群、神经退行性疾病和心血管疾病,总体研究趋势为进一步明确DR的抗炎机制,寻找新的治疗靶点,将更多经过体外和动物模型证实的有效方案进行更严格的临床试验。Objective:To conduct visualization analysis on the literature on dietary restriction(DR)regulating inflammation based on CiteSpace and VOSviewer visualization software,and to explore research hotspots and trends in this field.Methods:The literature on DR regulation inflammation in Web of Science core databases from January 12010 to September 292022 were searched.CiteSpace and VOSviewer visualization software was used to conduct quantitative and visual analysis of the annual publication volume,countries,institutions,authors,citation frequency and keywords of the retrieved literature.Results:A total of 1344 papers related to the topic were included,and the annual number of papers was generally on the rise,with the highest citation frequency of 1676 times.The United States(481 papers)is the country with the largest number of publications,followed by China(181 papers).The research hotspots in this field focused on calorie restriction(CR),ketogenic diet,aging,metabolic diseases,adipose tissue and gut microbiota.Conclusion:DR regulation of inflammation is increasingly favored by international and domestic researchers,and future research hotspots may be CR mimics(CRMs),intestinal microbiota,neurodegenerative diseases and cardiovascular diseases.The overall research trend is to further clarify the antiinflammatory mechanism of DR,find new therapeutic targets,and conduct more rigorous clinical trials with more effective regimens that have been proven in vitro and animal models.

关 键 词：饮食限制(DR) 热量限制(CR) 炎症 衰老 可视化分析 

分 类 号：R151.4[医药卫生—营养与食品卫生学]