鼻咽癌的自适应放疗及研究进展  

Research progress in adaptive radiation therapy of nasopharyngeal carcinoma

作　　者：王藤 高瀚 张彬 翟振宇[1] 郭文杰[1] 何侠[1,2,3] 尹丽[1,2,3] Wang Teng;Gao Han;Zhang Bin;Zhai Zhenyu;Guo Wenjie;He Xia;Yin Li(The Affiliated Cancer Hospital of Nanjing Medical University/Jiangsu Cancer Hospital/Jiangsu Institute of Cancer Research,Nanjing 210009,China;The Fourth School of Clinical Medicine,Nanjing Medical University,Nanjing 210000,China;Collaborative Innovation Center for Cancer Personalized Medicine,Nanjing Medical University,Nanjing 210000,China)

机构地区：[1]南京医科大学附属肿瘤医院/江苏省肿瘤医院/江苏省肿瘤防治研究所,南京210009 [2]南京医科大学第四临床医学院,南京210000 [3]南京医科大学肿瘤个体化医学协同创新中心,南京210000

出　　处：《中华放射肿瘤学杂志》2024年第6期562-566,共5页Chinese Journal of Radiation Oncology

基　　金：江苏省卫生健康委员会面上项目(M2022108);南京医科大学肿瘤个体化医学省部共建协同创新中心基金(JZ21449020210616)。

摘　　要：鼻咽癌是常见的头颈部肿瘤之一,调强放疗(IMRT)为目前的主要根治手段。精准放疗研究领域近年关注于自适应放疗(ART)。ART技术可减小因患者体重减轻、摆位误差、系统误差造成的患者靶区和危及器官剂量分布变化。此外,ART技术也可减轻因病灶及危及器官随着治疗发生解剖学变化等因素造成的患者靶区和危及器官实际接受剂量的变化,从而提高调强放疗的有效性和安全性。本文重点关注并总结鼻咽癌近年ART的相关研究进展,并提出未来的可能研究方向。Nasopharyngeal carcinoma is one of the most common head and neck tumors.At present,intensity modulated radiation therapy(IMRT)is the main radical treatment.In recent years,adaptive radiation therapy(ART)becomes the focus in the research field of precision radiotherapy.ART can reduce the target conformal and dose changes and increase the dose of exposed organs caused by factors such as weight loss,positioning error,systematic error,and anatomical changes of lesions and organs at risk,thus improving the effectiveness and safety of intensity modulated radiotherapy.This article focuses on and summarizes the recent progress in the application of ART in nasopharyngeal carcinoma,and puts forward the possible research direction in the future.

关 键 词：鼻咽肿瘤 放射疗法 调强 放射疗法 自适应 再计划 

分 类 号：R739.63[医药卫生—肿瘤]