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作 者:张白莎(综述) 汤丽平[1] 罗娜(审校)[2] ZHANG Baisha;TANG Liping;LUO Na(Department of Gastroenterology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400042,China;Department of Critical Care Medicine,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400042,China)
机构地区:[1]重庆医科大学附属第一医院消化内科,重庆400042 [2]重庆医科大学附属第一医院重症医学科,重庆400042
出 处:《现代医药卫生》2024年第12期2094-2098,共5页Journal of Modern Medicine & Health
基 金:重庆市科卫联合医学科研面上项目(2021MSXM044)。
摘 要:重症急性胰腺炎(SAP)是急性胰腺炎(AP)最严重的类型,是临床常见危重症,随着医疗水平不断提升,SAP早期死亡率明显降低,死亡高峰期主要集中在发病后期,而后期死亡原因主要是胰腺或胰周坏死感染后继发脓毒症,若能早期预测SAP继发脓毒症的风险,则可指导医务人员进行恰当的早期监测和干预,从而改善患者临床结局。该文综述了血液标志物对预测SAP继发脓毒症的应用进展。Severe acute pancreatitis(SAP)is the most serious type of acute pancreatitis(AP)and a common critical disease in clinic.With the continuous improvement of medical level,the mortality rate in the early stage of SAP has decreased significantly,and the peak of death is mainly concentrated in the later stage of the disease,and the main cause of death in the later stage is secondary sepsis after infection of pancreatic or peripancreatic necrosis.If the risk of secondary sepsis in SAP can be predicted early,it can guide the medical staff to carry out appropriate early monitoring and intervention to improve the clinical outcome of patients.The article reviewed the application progressof blood markers to predict secondary sepsis in SAP.
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