青年急性缺血性卒中病因分型及危险因素的性别差异研究  

Study on the Gender Difference of Etiological Types and Risk Factors of Acute Ischemic Stroke in Young People

作　　者：张瑞锋 罗小娜 冯丽君[1] 张晓曼[1] ZHANG Rui-feng;LUO Xiao-na;FENG Li-jun;ZHANG Xiao-man(Department of Neurology,the First People's Hospital of Zhengzhou,Zhengzhou 450004,Henan Province,China)

机构地区：[1]郑州市第一人民医院神经内科,河南郑州450004

出　　处：《罕少疾病杂志》2024年第6期15-17,共3页Journal of Rare and Uncommon Diseases

基　　金：河南省医学科技攻关计划联合共建项目(LHGJ20190987)-3.0T高分辨磁共振对青年卒中大脑中动脉M1段斑块分析研究。

摘　　要：目的 探讨青年缺血性卒中危险因素及比较不同性别青年缺血卒中差别。方法 将2017年1月-2020年1月于郑州市第一人民医院神经内科住院的青年急性缺血性卒中患者作为研究对象,收集相关资料,根据性别分组分析。 结果 218例青年卒中患者,男性165例(75.7%),女性53例(24.3%),平均年龄(38.6±5.4)岁,常见前3名危险因素依次为:高血压143例(65.6%),血脂异常110例(50.5%),卒中病史97例(44.5%)。TOAST分型显示最常见类型为大动脉粥样硬化型128例(58.7%)。男女组间高血压、血脂异常、吸烟、饮酒、高同型半胱氨酸血症、贫血、高尿酸血症比例方面有明显差异(P<0.05)。TOAST分型中女性患者其他原因型远远高于男性患者(22.6%vs 4.8%)(P<0.05)。结论 高血压,高脂血症,吸烟,高同型半胱氨酸血症等可控性危险因素仍是青年缺血性卒中主要危险因素,青年缺血性卒中患者不同性别危险因素和病因分型有所差异。Objective To investigate the risk factors with ischemic stroke in youth and to compare the differences between different sexes and different parts in young adults with ischemic stroke.MethodsThe young patients with acute ischemic stroke who were admitted in the Department of Neurology of the First People's Hospital of Zhengzhou City from January 2017 to January 2020 were collected.Clinical data,laboratory data,and National Institutes of Health Stroke Stroke scores,location and etiology were documented.ResultsOf the 218 young stroke patients,165 were male(75.7%),53 were female(24.3%),and the average age was(38.6±5.4)years old.The top five common risk factors were:143 patients with hypertension(65.6%),110 patients with hyperlipidemia(50.5%),97 cases of stroke history(44.5%).TOAST classification showed that the most common type was 128 cases(58.7%)of atherosclerosis.There were significant differences in the proportions of hypertension,dyslipidemia,smoking,alcohol consumption,hyperhomocysteinemia,anemia,and hyperuricemia between male and female groups(P<0.05).The TOAST classification of female patients with other causes is much higher than that of male patients(22.6%vs 4.8%),and has clinical significance(P<0.05).Conclusion Controllable risk factors such as hypertension,hyperlipidemia,smoking,and hyperhomocysteinemia are the main risk factors for ischemic stroke in young people.Youth ischemic stroke patients with different genders and before and after circulation young ischemia The risk factors and etiology of sexual stroke are different.

关 键 词：缺血性卒中 青年 危险因素 性别 

分 类 号：R743.3[医药卫生—神经病学与精神病学]