DWI诊断肿块型胰腺炎及胰腺癌的价值观察  

Value of DWI in the Diagnosis of Mass Forming Pancreatitis and Pancreatic Cancer

作　　者：樊琦 王强荣[1] 顾菲 孔琳 常春[1] 周健文 姜小兰 汤泽宇 FAN Qi;WANG Qiang-rong;GU Fei;KONG Lin;CHANG Chun;ZHOU Jian-wen;JIANG Xiao-lan;TANG Ze-yu(Department of Radiology,Dongtai People's Hospital,Dongtai 224200,Jiangsu Province,China;Department of Clinical Laboratory,Dongtai People's Hospital,Dongtai 224200,Jiangsu Province,China)

机构地区：[1]东台市人民医院影像科,江苏东台224200 [2]东台市人民医院检验科,江苏东台224200

出　　处：《中国CT和MRI杂志》2024年第6期118-120,共3页Chinese Journal of CT and MRI

基　　金：中国医药卫生事业发展基金会项目(C202212-025);2023年度东台市医疗卫生领域科技计划项目(DTYW2023006)。

摘　　要：目的 观察DWI诊断肿块型胰腺炎及胰腺癌的价值。方法 以2020年3月—2023年3月东台市人民医院影像科接受检查的肿块型胰腺炎及胰腺癌96例为研究对象,根据病历资料分为肿块型胰腺炎41例(胰腺炎组)、胰腺癌55例(胰腺癌组)。比较两组影像学特征、表观弥散系数(ADC)值,并进行肿块型胰腺炎及胰腺癌鉴别诊断的二元Logistic分析,受试者工作特征曲线分析常规DWI及ADC值对胰腺癌鉴别诊断效能。结果 胰腺癌组T_(2)WI混杂高信号占比明显高于胰腺炎组(P<0.05).胰腺癌组ADC值明显高于胰腺炎组(P<0.05)。二元Logistic分析显示T_(2)WI混杂高信号、ADC值是肿块型胰腺炎及胰腺癌鉴别诊断的独立影响因素(P<0.05)。常规DWI联合ADC值对胰腺癌鉴别诊断的AUC为0.843、特异度92.1%较两者单项诊断的高。结论 DWI对肿块型胰腺炎及胰腺癌的鉴别诊断有一定价值,有望为胰腺癌早期诊治提供必要参考。Objective To observe the value of DWI in the diagnosis of mass forming pancreatitis(MFP) and pancreatic cancer.Methods The medical records of 41 patients with MFP and 55 patients with pancreatic cancer who were examined in Imaging Department of Dongtai People s Hospital from Ma rch 2020 to Ma rch 2023 were analyzed.Imaging cha racteristics and appa rent diffusion coefficient(ADC) values of the two groups were compared.Binary logistic analysis of the differential diagnosis of MFP and pancreatic cancer was conducted.The performance of conventional DWI and ADC value in diagnosing pancreatic cancer was analyzed using the receiver operating characteristic curve.Results The proportion of mixed high signal on T_(2WI) in pancreatic cancer group was significantly higher than that in pancreatitis group(P<0.05).ADC value in pancreatic cancer group was significantly higher than that in pancreatitis group(P<0.05).Bina ry logistic analysis showed that mixed with high signal on T_(2WI) and ADC value were independent influencing factors for differential diagnosis of MFP and pancreatic cancer(P<0.05).The AUC and specificity of conventional DWI combined with ADC value in diagnosing pancreatic cancer were 0.843 and 92.1%,higher than those of single diagnosis.Conclusion DWI is helpful for differential diagnosis of MFP and pancreatic cancer.It is expected to provide reference for early diagnosis and treatment of pancreatic cancer.

关 键 词：胰腺癌 肿块型胰腺炎 DWI 鉴别诊断 

分 类 号：R735.9[医药卫生—肿瘤]