Review on the application of upconversion nanomaterials in heavy metal detection  

作　　者：Yu-Hong He Xi Yu 

机构地区：[1]Faculty of Traditional Chinese Medicine,Macao University of Science and Technology,Macao,China.2 Faculty of Medicine,Macao University of Science and Technology,Macao,China

出　　处：《Food and Health》2024年第3期1-17,共17页食品和健康（英文）

基　　金：supported by the Science and Technology Development Fund,Macao SAR(Grant 0065/2023/ITP2).

摘　　要：As a widespread element,heavy metals have a significant impact on human health and threaten human health.It is of great significance to develop analytical technologies that can detect heavy metal ions quickly and accurately.In comparison to conventional fluorescent materials such as organic dyes,quantum dot(QD)labels,and carbon quantum dots(CD),fluorescence detection technology utilizing lanthanide(Ln)ion-doped upconversion nanoparticles(UCNPs)stands out due to its distinctive attributes.These include a notably reduced autofluorescence background,enhanced tissue penetration capabilities,biocompatibility with cellular tissues,and minimal photodamage inflicted on biological samples.The utilization of this technology has garnered considerable attention across multiple fields.In the domain of heavy metal detection,traditional laboratory methods necessitate costly instrumentation and a fully equipped laboratory,involving intricate sample processing procedures and protracted detection periods,as well as a demand for skilled personnel.In contrast,the implementation of this material offers rapid and cost-effective detection,significantly mitigating the technical barriers for operators.Consequently,this represents an exceptional avenue to curtail expenses and broaden the scope of detection within the analytical process.This paper reviews the research progress of UCNPs in the detection of heavy metal ions,encompassing a brief elucidation of the luminescence principle of upconversion nanomaterials and commonly used detection principles.Additionally,it provides a detailed overview of the research status of several common non-metal ions and essential heavy metals.Furthermore,it summarizes the current focal points in UCNP detection and discusses the challenges and prospects associated with it.

关 键 词：Heavy metals Upconversion nanoparticles Gold nanoparticles NANOSENSOR Fluorescence detection technology 

分 类 号：R73[医药卫生—肿瘤]