肾移植术后肺部小孢根霉感染1例  

A case of pulmonary Rhizopus microporus infection after kidney transplantation

作　　者：孙东 王凯[1] 王振璞 曲青山 SUN Dong;WANG Kai;WANG Zhenpu;QU Qingshan(The Fifth Clinical Medical College of Henan University of Chinese Medicine(Zhengzhou People's Hospital),Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第五临床医学院(郑州人民医院),郑州450003

出　　处：《中国真菌学杂志》2024年第2期169-172,共4页Chinese Journal of Mycology

摘　　要：报道1例肾移植术后肺部小孢根霉感染。患者,男,45岁,2021年9月20日因“肾移植术后5个月余,发热5 d”为主诉入院。通过微生物(肺泡灌洗液)二代基因测序检查提示小孢根霉,临床诊断为肺部真菌(小孢根霉)感染,使用两性霉素B脂质体+泊沙康唑治疗,肺部感染症状逐渐好转,8周后病情稳定后出院,移植肾功能较前明显下降,截止到随访终点移植肾功能尚未恢复。Report on a case of pulmonary infection caused by Rhizopus microporus after kidney transplantation.The patient,male,45 years old,was admitted on September 20,2021 due to the chief complaint of fever for more than 5 months after kidney transplantation.Through second-generation gene sequencing of microorganisms(bronchoalveolar lavage fluid),he was found that Rhizopus microporus was infected with diagnosed with pneumonia caused by Rhizopus microporus.Clinical diagnosis was made,and treatment with amphotericin B liposomes and posaconazole gradually improved the symptoms of pulmonary infection.After 8 weeks of stable condition,the patient was discharged from the hospital,and the transplanted kidney function significantly decreased compared to before.As of the follow-up endpoint,the transplanted kidney function has not yet recovered.

关 键 词：肾移植 肺部感染 小孢根霉 毛霉 移植肾功能 

分 类 号：R519.8[医药卫生—内科学]