恶性潜能未定的子宫平滑肌瘤诊治的中国专家共识(20242024年版年版)  

Chinese expert consensus on the diagnosis and treatment of uterine smooth muscle tumor of uncertain malignant potential(2024 Edition)

作　　者：中国医师协会微无创医学专业委员会妇科肿瘤学组 中国优生科学协会肿瘤生殖学分会 山东省康复医学会妇科肿瘤康复分会 王雅卓 王健[3] 王建东[4] 王玉东[5] 刘从容[6] 范江涛 刘淑娟 张颐[9] 张师前[10] Gynecologic Oncology Group of Minimally-Invasive and Noninvasive Medicine Committee of Chinese Medical Doctor Association;Reproductive Oncology Branch of China Healthy Birth Science Association;Gynecologic Oncology Rehabilitation Branch of Shandong Association of Rehabilitation Medicine

机构地区：[1]不详 [2]河北省人民医院 [3]济宁医学院附属枣庄市立医院 [4]首都医科大学附属北京妇产医院 [5]上海交通大学医学院附属国际和平妇幼保健院 [6]北京大学第三医院 [7]广西医科大学第一附属医院 [8]空军军医大学第一附属医院 [9]中国医科大学附属第一医院 [10]山东大学齐鲁医院

出　　处：《癌症进展》2024年第9期929-936,共8页Oncology Progress

基　　金：辽宁省应用基础研究计划项目(2022JH2/101300039);2022年沈阳市科技计划项目(22-321-33-08)。

摘　　要：恶性潜能未定的子宫平滑肌瘤(STUMP)是一类区别于子宫平滑肌瘤和子宫平滑肌肉瘤的子宫交界性/中间型肿瘤,发病率较低,虽然预后较好,但仍存在一定的复发、恶变风险。STUMP的临床表现及影像学特征均缺乏特异性,主要依靠术后病理学检查确诊,目前STUMP尚无统一的病理检查诊断标准,组织形态学联合免疫组化及分子检测有助于诊断及预后判断。无生育需求者推荐行子宫切除术,有生育需求者在充分知情同意并评估风险后,可选择STUMP病灶切除术,完成生育后行子宫切除术,术后密切随访。Uterine smooth muscle tumor of uncertain malignant potential(STUMP)is a borderline/intermediate uter-us tumor distinguished from benign uterine leiomyoma and malignant uterine leiomyosarcoma,with a low incidence rate.Although the prognosis is good,there is still a particular risk of recurrence and malignancy.Lacking specificity in clinical manifestations and imaging features,the diagnosis of STUMP mainly relies on postoperative pathological examination.Currently,there are no unified pathologically diagnostic standards for STUMP.The combination of organizational mor-phology,immunohistochemistry,and molecular detection is helpful for diagnosis and prognosis prediction.Hysterectomy is recommended for STUMP patients without fertility desire,lesion resection surgery under comprehensive risk assess-ment could be an option for those who have fertility needs when close follow-up could be guaranteed.However,a com-plete hysterectomy still needs to be performed after delivery.

关 键 词：恶性潜能未定的子宫平滑肌瘤 诊断 治疗 专家共识 

分 类 号：R737.33[医药卫生—肿瘤]