A commentary of“Rhythmic cilia changes support SCN neuron coherence in circadian clock”:Top 10 Scientific Advances of 2023,China  

作　　者：Wei Li Guangshuo Ou 

机构地区：[1]School of Medicine,Tsinghua University,Beijing 100084,China [2]Tsinghua-Peking Center for Life Sciences,Beijing Frontier Research Center for Biological Structure,McGovern Institute for Brain Research,State Key Laboratory of Membrane Biology,School of Life Sciences and MOE Key Laboratory for Protein Science,Tsinghua University,Beijing 100084,China

出　　处：《Fundamental Research》2024年第3期695-696,共2页自然科学基础研究（英文版）

摘　　要：Primary cilia,microtubule-based cellular protrusions found on the surface of nearly all eukaryotic cells,serve as crucial signaling hubs[1].These antenna-like organelles play a pivotal role in perceiving environmental stimuli,thereby orchestrating cellular behavior and fate.Primary cilia are essential for various signaling pathways,including the Sonic Hedgehog(SHH)pathway.Ciliary dysfunction can affect multiple organ systems and manifest as a spectrum of genetic disorders collectively termed as ciliopathies.However,until recently,their involvement in circadian rhythms was unknown.

关 键 词：Primary INVOLVEMENT COLLECTIVE 

分 类 号：G322[文化科学]