A commentary of“Novel approaches in precise genome manipulations from single nucleotides to large DNA segments”:Top 10 Scientific Advances of 2023,China  

作　　者：Xiaofeng Cao 

机构地区：[1]Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101,China

出　　处：《Fundamental Research》2024年第3期699-700,共2页自然科学基础研究（英文版）

摘　　要：The life sciences field has experienced profound impacts from genome editing,a technology that enables precise genetic sequence modifications in living cells.Developments in genome editing have significantly propelled advances in biomedicine and agricultural breeding.With the introduction of CRISPR as a genome editing tool in 2012[1],rapid progress has paved the way for emerging technologies such as base editing and prime editing[2,3].These sophisticated editing methods facilitate more accurate genome modifications and promise to profoundly impact the future of precision medicine,crop improvement,and even the de novo design of organisms.

关 键 词：PRECISE EDITING manipulation 

分 类 号：Q78[生物学—分子生物学]