Insights into the mechanism of L-malic acid on drip loss of chicken meat under commercial conditions  

作　　者：Haijun Sun Xue Yan Lu Wang Ruimin Zhu Meixia Chen Jingdong Yin Xin Zhang 

机构地区：[1]State Key Laboratory of Animal Nutrition and Feeding,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China [2]New Hope Liuhe Co.,Ltd./Key Laboratory of Feed and Livestock and Poultry Products Quality&Safety Control,Ministry of Agriculture,Chengdu,Sichuan 610023,China [3]Institute of Animal Husbandry and Veterinary Medicine,Beijing Academy of Agriculture and Forestry Sciences,Beijing 100097,China

出　　处：《Journal of Animal Science and Biotechnology》2024年第3期1312-1324,共13页畜牧与生物技术杂志（英文版）

基　　金：This study was funded by the Key Laboratory of Feed and Livestock and Poultry Products Quality&Safety Control,Ministry of Agriculture(2021202201);Reform and Development Project of BAAFS(XMS202322).

摘　　要：Background A deterioration in the meat quality of broilers has attracted much more attention in recent years.L-malic acid(MA)is evidenced to decrease meat drip loss in broilers,but the underlying molecular mechanisms are still unclear.It’s also not sure whether the outputs obtained under experimental conditions can be obtained in a com-mercial condition.Here,we investigated the effects and mechanisms of dietary MA supplementation on chicken meat drip loss at large-scale rearing.Results Results showed that the growth performance and drip loss were improved by MA supplementation.Meat metabolome revealed that L-2-aminoadipic acid,β-aminoisobutyric acid,eicosapentaenoic acid,and nicotinamide,as well as amino acid metabolism pathways connected to the improvements of meat quality by MA addition.The transcriptome analysis further indicated that the effect of MA on drip loss was also related to the proper immune response,evidenced by the enhanced B cell receptor signaling pathway,NF-κB signaling pathway,TNF signaling pathway,and IL-17 signaling pathway.Conclusions We provided evidence that MA decreased chicken meat drip loss under commercial conditions.Metabolome and transcriptome revealed a comprehensive understanding of the underlying mechanisms.Together,MA could be used as a promising dietary supplement for enhancing the water-holding capacity of chicken meat.

关 键 词：Drip loss Immune response L-malic acid Meat quality METABOLOME TRANSCRIPTOME 

分 类 号：S831.5[农业科学—畜牧学]