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作 者:张爱华[1] 许萌[1] 杨宇英 马丹丹[1] 程俊伟[1] 张歌 任鹏飞[1] 江华[2] ZHANG Aihua;XU Meng;YANG Yuying;MA Dandan;CHENG Junwei;ZHANG Ge;REN Pengfei;JIANG Hua(Henan Infectious Diseases Hospital(The Sixth People's Hospital of Zhengzhou City),Zhengzhou 450015,Henan,China;School of Nursing,Peking University,Beijing 100191,China)
机构地区:[1]河南省传染病医院(郑州市第六人民医院),郑州450015 [2]北京大学护理学院,北京100191
出 处:《中国艾滋病性病》2024年第4期372-376,共5页Chinese Journal of Aids & STD
基 金:河南省医学科技攻关计划联合共建项目(LHGJ20191097)。
摘 要:目的 分析河南省艾滋病合并结核病患者的营养风险发生情况及影响因素。方法 回顾性收集2019年1月至2022年12月在河南省某传染病专科医院住院的711例艾滋病合并结核病患者的临床病例资料,分析其营养风险发生情况及其影响因素。结果 河南省711例艾滋病合并结核病患者营养风险发生率为70.3%(500例)。年龄>60岁(OR=2.609,95%CI:1.375~4.949)、有吸烟史(OR=2.411,95%CI:1.617~3.595)、痰涂片/培养阳性(OR=1.919,95%CI:1.200~3.067)的患者营养风险发生率较高,居住地非农村(OR=0.125,95%CI:0.031~0.500)、HIV感染确诊时长≥6个月(OR=0.532,95%CI:0.336~0.844)、CD4细胞计数>200个/μL(OR=0.191,95%CI:0.095~0.383)的患者营养风险发生率较低(P<0.05)。结论 河南省艾滋病合并结核病患者营养风险的发生比例较高,应重点关注年龄>60岁、有吸烟史、居住在农村、HIV感染确诊时长<6个月、痰涂片/培养阳性、CD4细胞计数≤200个/μL的患者,为其制定并实施科学、合理的干预措施,以降低营养风险发生率。Objective To analyze the characteristics and influencing factors of nutritional risk among AIDS patients with tuberculosis in Henan Province. Methods The clinical data of 711 AIDS patients with tuberculosis admitted to Henan Provincial Infectious Disease Hospital from January 2019 to December 2022 were retrospectively collected. The characteristics and influencing factors of nutritional risk were analyzed. Results The incidence of nutritional risk was 70.3%(500 cases) among the 711 AIDS patients with tuberculosis in Henan Province. The results of multivariate regression analysis showed that patients aged >60 years(OR=2.609, 95%CI: 1.375-4.949), with a history of smoking(OR=2.411, 95%CI: 1.617-3.595), and positive for sputum smear/culture(OR=1.919, 95%CI: 1.200-3.067) had a higher incidence of nutritional risk. Patients living in non-rural areas(OR=0.125, 95%CI: 0.031-0.500), with a HIV infection diagnosis time of ≥6 months(OR=0.532, 95%CI: 0.336-0.844), and with a CD4+T lymphocyte count >200 cells/μL(OR=0.191, 95%CI: 0.095-0.383) had a lower incidence of nutritional risk( P<0.05). Conclusions The nutritional risk of AIDS patients with tuberculosis in Henan Province was relatively high. More attention should be paid to patients with age >60 years, history of smoking, rural residence, HIV infection diagnosis time <6 months, positive sputum smear/culture, and CD4+T lymphocyte count ≤200 cells/μL. Scientific and reasonable intervention measures should be formulated and implemented among such patients to decrease the incidence of nutritional risk.
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