耳穴压丸联合光疗治疗轻中度抑郁症的临床研究  

Clinical efficacy of auricular point pressing therapy combined with light therapy on mild to moderate depression

作　　者：唐捷怡 梁泳彤 郑美鸿 黎焕杰 刘继洪 TANG Jieyi;LIANG Yongtong;ZHENG Meihong;LI Huanjie;LIU Jihong(Guangzhou University of Chinese Medicine,Guangzhou 510405,Guangdong,China;Foshan Hospital of Traditional Chinese Medicine,Foshan 528000,Guangdong,China;Dali Town Community Health Service Center,Foshan 528000,Guangdong,China)

机构地区：[1]广州中医药大学,广东广州510405 [2]广州中医药大学附属佛山中医院,广东佛山528000 [3]佛山市南海区大沥镇社区卫生服务中心,广东佛山528000

出　　处：《现代中西医结合杂志》2024年第10期1370-1375,1395,共7页Modern Journal of Integrated Traditional Chinese and Western Medicine

基　　金：广东省中医药局科研项目(20211368)。

摘　　要：目的 比较耳穴压丸联合光疗、耳穴压丸与艾司西酞普兰治疗轻中度抑郁症的临床疗效。方法 将2021年4月—2023年6月在佛山市中医院就诊的96例轻中度抑郁症患者随机分为耳穴压丸联合光疗组(32例,脱落2例)、耳穴压丸组(32例,脱落1例)和西药组(32例,脱落1例)。耳穴压丸联合光疗组给予抑郁症光疗灯具光照(光照强度10 000 lux,每次治疗30 min,每周治疗5次)及单侧耳穴王不留行籽贴压(每周治疗1次,双耳交替)治疗,耳穴压丸组给予单侧耳穴王不留行籽贴压治疗,西药组给予艾司西酞普兰10 mg/d口服,3组均治疗2个月。比较3组患者治疗前后汉密尔顿抑郁量表24项版本(HAMD-24)评分、生活质量量表(SF-36)评分、抑郁自评量表(SDS)评分、一般自我效能感量表(GSES)评分,并评定3组临床疗效。结果 与治疗前比较,3组患者治疗后HAMD-24总分、SDS评分均明显降低(P均<0.05),SF-36量表中生理机能、生理职能、精力、情感职能、精神健康评分及GSES评分均明显升高(P均<0.05);耳穴压丸联合光疗组HAMD-24总分、SDS评分降低幅度和HAMD-24量表中阻滞、认知障碍、日夜变化评分降低幅度均明显大于耳穴压丸组和西药组(P均<0.05),SF-36量表中生理机能、情感职能评分升高幅度均明显大于耳穴压丸组和西药组(P均<0.05),各组GSES评分升高幅度比较差异均无统计学意义(P均>0.05)。耳穴压丸联合光疗组治疗总有效率明显高于耳穴压丸组和西药组[96.7%(29/30)比71.0%(22/31)、71.0%(22/31),P均<0.05]。结论 耳穴压丸联合光疗可明显减轻轻中度抑郁症患者抑郁程度,治疗总体效果优于单纯光疗和西药治疗。Objective It is to compare the clinical efficacies of auricular point pressing combined with light therapy,auricular point pressing and escitalopram in the treatment of mild to moderate depression.Methods Ninety-six patients with mild to moderate depression treated in Foshan Hospital of Traditional Chinese Medicine from April 2021 to June 2023 were randomly divided into auricular point pressing combined with light therapy group(combination group,n=32,2 cases dropped),auricular point pressing group(n=32,1 case dropped),and the western medicine group(n=32,1 case dropped).The combination group was treated with light therapy with depression light-therapy lamp(light intensity 10000 lux,30 min per time,5 times per week)and unilateral auricular point pressing with Cowherb Seed(1 time per week,alternating between bilateral ears),the auricular point pressing group was treated with unilateral auricular point pressing with Cowherb Seed,and the western medicine group was treated with escitalopram orally,10 mg/d,all the three groups were treated for 2 months.The scores of Hamilton Depression Scale 24-item version(HAMD-24),Short Form 36 Questionnaire(SF-36),Self-Depression Scale(SDS)and General Self-Efficacy Scale(GSES)of patients before and after the treatment were compared among the three groups,and the clinical efficacies of the three groups were assessed.Results Compared with those before treatment,the total scores of HAMD-24 and SDS scores of the three groups were significantly reduced after treatment(all P<0.05),and their scores of physiological function,physiological role,energy,emotional role,mental health of SF-36 and GSES scores were significantly increased(all P<0.05);the decreases of total scores of HAMD-24 and SDS scores,and the scores of block,cognitive impairment,day-night change of HAMD-24 were more significant in the combination group than those in the auricular point pressing group and western medicine group(all P<0.05),while the increases of the scores of physiological function and emotional role of SF-36 we

关 键 词：轻中度抑郁症 光疗 耳穴压丸 

分 类 号：R749.4[医药卫生—神经病学与精神病学]