不同一次性根管治疗在不可逆性牙髓炎患者中的应用研究  

A study on the application of different one-time root canal treatments in patients with irreversible pulpitis

作　　者：雷诗鑫 魏佳涵 胡淳[1] 谭劲[1] LEI Shixin;WEI Jiahan;HU Chun;TAN Jin(Department of Stomatology,the First Affiliated Hospital of Hunan University of Chinese Medicine,Hunan,Changsha 410000,China)

机构地区：[1]湖南中医药大学第一附属医院口腔科,湖南长沙410000

出　　处：《中国医药科学》2024年第11期172-176,共5页China Medicine And Pharmacy

基　　金：国家自然科学基金委员会资助项目(面上项目)(81874496)。

摘　　要：目的探讨不同一次性根管治疗对不可逆性牙髓炎患者疼痛程度及止痛干预的影响。方法选择2020年7月至2023年1月湖南中医药大学第一附属医院收治的100例不可逆性牙髓炎患者,按照随机数表法分为三组,其中33例接受热牙胶垂直加压(TSCC)填充治疗,34例接受冷牙胶自由压实(CFFC)治疗,33例接受冷牙胶侧方加压(CLC)治疗。比较三组患者疼痛程度、止痛干预相关指标、术后填充质量及炎症因子水平。结果术后2、6 h三组患者视觉模拟评分法(VAS)评分均降低,其中CFFC组VAS评分低于CLC组、TSCC组,差异有统计学意义(P<0.05);术后3 d,CFFC组用药剂量、频次少于其他两组,起效时间短于其他两组,差异有统计学意义(P<0.05);治疗后三组患者适充率比较,差异有统计学意义(P<0.05);治疗后CFFC组适充率为91.18%,显著高于其他两组,差异有统计学意义(P<0.05);术后三组炎症因子水平均下降(P<0.05),其中CFFC组白细胞介素-6、白细胞介素-1β、C反应蛋白水平明显低于其他两组,差异有统计学意义(P<0.05)。结论不可逆性牙髓炎患者实施TSCC及CFFC治疗后疼痛明显减轻且术后填充质量优秀,其中CFFC技术在缩短止痛干预起效时间及减少止痛药物摄入方面效果良好,可降低患者炎症因子水平。Objective To explore the effects of different one-time root canal treatments on pain severity and pain relief interventions in patients with irreversible pulpitis.Methods A total of 100 patients with irreversible pulpitis admitted to the First Affiliated Hospital of Hunan University of Chinese Medicine from July 2020 to January 2023 were randomly divided into three groups using a random number table method.Among them,33 patients received thermoplasticised solid-core compaction(TSCC)filling treatment,34 patients received cold free-flow compaction(CFFC)treatment,and the other 33 patients received cold lateral compaction(CLC)treatment.The degree of pain,pain relief intervention-related indicators,postoperative filling quality,and levels of inflammatory factors among the three groups of patients were compared.Results The visual analogue scale(VAS)scores of the three groups of patients decreased at 2 and 6 hours after surgery,with lower VAS scores in the CFFC group than in the CLC group and TSCC group,with statistically significant differences(P<0.05).Three days after surgery,the dosage and frequency of medication in the CFFC group were lower than those in the other two groups,and the onset time was shorter than the other two groups,with statistically significant differences(P<0.05).After treatment,there was statistically significant difference in adaptation rate among patients in the three groups(P<0.05).After treatment,the adaptation rate of the CFFC group was 91.18%,which was significantly higher than the other two groups,with statistically significant differences(P<0.05).After surgery,the levels of inflammatory factors in all three groups decreased(P<0.05),with the levels of interleukin-6,interleukin-1βand C-reactive protein significantly lower than the other two groups,with statistically significant differences(P<0.05).Conclusion The pain of patients with irreversible pulpitis who were treated with TSCC or CFFC was significantly reduced with excellent postoperative filling quality.Among them,the CFFC has good ef

关 键 词：不可逆性牙髓炎 自由压实法 垂直加压法 侧方加压法 牙胶 疼痛程度 

分 类 号：R781.31[医药卫生—口腔医学]