Bio-Oss骨粉与CGF在自体牙移植游离端骨缺损中的修复重建  

Repair and reconstruction of bone defects in autogenous tooth transplantation using Bio-Oss bone powder combined with concentrated growth factor

作　　者：张翠乐 陈志方 赵璐 ZHANG Cui-le;CHEN Zhi-fang;ZHAO Lu(Hefei School of Oral Clinical,Anhui Medical University,the Fifth Clinical College of Anhui Medical University,Department of Oral Srugery,West District of Hefei Stomatological Hospital,Hefei 230001,Anhui,China)

机构地区：[1]安徽医科大学合肥口腔临床学院、安徽医科大学第五临床学院、合肥市口腔医院西区口腔外科,安徽合肥230001

出　　处：《广东医学》2024年第6期777-781,共5页Guangdong Medical Journal

基　　金：2022年合肥市口腔医院院级重点科研项目(院级教[2022]45号04)。

摘　　要：目的评估Bio-Oss骨粉和浓缩生长因子(concentrated growth factor,CGF)联合应用于自体牙移植游离端骨缺损修复的临床疗效。方法选取2018年7月至2022年6月就诊于合肥市口腔医院口腔外科患者共44例,观察组23例,术中应用Bio-Oss骨粉及CGF;对照组21例,不应用任何材料,术后定期随访,对比移植牙术后即刻初期稳定性、术后1周牙龈状况、术后3个月和6个月骨愈合情况以及术后1年成功率。结果观察组移植牙术后即刻初期稳定性较对照组有明显改善,差异有统计学意义(P<0.05);观察组术后1周牙龈肿胀度与对照组无明显改善,差异无统计学意义(P>0.05);术后3个月受牙区牙槽骨愈合情况较对照组好,差异有统计学意义(P<0.05);术后随访1年,观察组牙移植成功率100%;对照组牙移植成功率90.5%,留存率95.2%,失败率4.8%,差异有统计学意义(P<0.05)。结论Bio-Oss骨粉与CGF在自体牙移植游离端骨缺损中有较好的临床疗效,促进新骨形成,有利于移植牙早期稳定,提高自体牙移植成功率。Objective To evaluate the clinical efficacy of Bio-Oss bone powder combined with concentrated growth factor(CGF)in repairing bone defects in autogenous tooth transplantation.Methods A total of 44 patients treated in the Department of Oral Surgery at Hefei Stomatological Hospital from July 2018 to June 2022 were selected.The observation group consisted of 23 patients who received Bio-Oss bone powder and CGF during surgery,while the control group consisted of 21 patients who did not receive any material.Patients were followed up regularly postoperatively.The immediate stability after tooth transplantation,gingival condition one week postoperatively,bone healing at three and six months postoperatively,and the success rate one year postoperatively were compared between the two groups.Results The immediate stability after tooth transplantation was significantly improved in the observation group compared to the control group,with a statistically significant difference(P<0.05).There was no significant improvement in gingival swelling one week postoperatively between the two groups(P>0.05).Bone healing at three months postoperatively was better in the observation group than in the control group,with a statistically significant difference(P<0.05).At one year follow-up,the success rate of tooth transplantation was 100%in the observation group and 90.5%in the control group,with a retention rate of 95.2%and a failure rate of 4.8%.The difference was statistically significant(P<0.05).Conclusion Bio-Oss bone powder combined with CGF has good clinical efficacy in repairing bone defects in autogenous tooth transplantation.It promotes new bone formation,facilitates early stability of the transplanted tooth,and improves the success rate of autogenous tooth transplantation.

关 键 词：自体牙移植 BIO-OSS骨粉 浓缩生长因子 游离端缺失 

分 类 号：R782.2[医药卫生—口腔医学]