碘125粒子食管支架与自膨支架在中晚期食管癌患者中的应用效果比较  

Comparison of the Application Effect of Iodine-125 Particle Esophageal Stent and Self-expanding Stent in Patients with Middle and Advanced Esophageal Cancer

作　　者：杨森[1] 吴林霖[1] 王伟[2] 胡苗苗[1] 张旭升[1] Yang sen;Wu Linlin;Wang Wei;Hu Miaomiao;Zhang Xusheng(Oncology Department,Tengzhou Central People's Hospital,Tengzhou 277500,Shandong Province,China;The Third Department of Oncology,Tengzhou Central People's Hospital,Tengzhou 277500,Shandong Province,China)

机构地区：[1]滕州市中心人民医院肿瘤一科,山东滕州277500 [2]滕州市中心人民医院肿瘤三科,山东滕州277500

出　　处：《中外医药研究》2024年第13期24-26,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：枣庄市科技发展计划项目(编号:2023NS39)。

摘　　要：目的:比较碘125粒子食管支架与自膨支架在中晚期食管癌患者中的应用效果。方法:选取2014年7月—2020年8月滕州市中心人民医院收治的中晚期食管癌患者82例作为研究对象,依据随机数字表法分为对照组(n=40)和观察组(n=42)。对照组接受覆膜自膨支架植入术,观察组接受碘125粒子食管支架植入术。比较两组吞咽困难程度、术后并发症发生情况、生存时间。结果:术前,两组Stooler分级比较,差异无统计学意义(P>0.05);术后6个月,两组Stooler分级降低,观察组低于对照组,差异有统计学意义(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。观察组生存时间长于对照组,差异有统计学意义(P<0.001)。结论:碘125粒子食管支架植入术用于中晚期食管癌患者效果优于覆膜自膨支架,能够有效缓解吞咽困难,延长生存时间,且未增加并发症发生风险。Objective:To compare the application effect of iodine 125 particle esophageal stent and self-expanding stent in patients with middle and advanced esophageal cancer.Methods:A total of 82 patients with middle and advanced esophageal cancer were selected as research objects at Tengzhou Central People's Hospital from July 2014 to August 2020,and were divided into control group(n=40)and observation group(n=42)according to random number table method.The control group received self-expanding stent implantation,and the observation group received iodine 125 particle esophageal stent implantation.The degree of dysphagia,postoperative complications and survival time were compared between the two groups.Results:Before operation,there was no significant difference in Stooler grading between the two groups(P>0.05);six months after operation,the Stooler grade of the two groups decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).The survival time of observation group was longer than that of control group,and the difference was statistically significant(P<0.001).Conclusion:Iodine 125 particle implantation of esophageal stents in patients with advanced esophageal cancer is more effective than coated self-expanding stents,which can effectively relieve dysphagia and prolong survival time without increasing the risk of complications.

关 键 词：食管癌 碘125粒子 覆膜自膨支架 中晚期 

分 类 号：R735.1[医药卫生—肿瘤]