iRoot BP plus与MTA根尖屏障术治疗年轻恒牙慢性根尖周炎的疗效比较  

Comparison of the effects of using iRoot BP plus and MTA apical barrier surgery in young permanent teeth with chronic apical periodontitis

作　　者：孙艳妮[1] 赵蕾 刘伟 殷晓萍 SUN Yan-ni;ZHAO Lei;LIU Wei;YIN Xiao-ping(Department of Stomatology,Qingdao Hiser Hospital,Affiliated to Qingdao University(Qingdao Traditional Chinese Medicine Hospital).Qingdao 266000;Department of Stomatology,Qingdao Central Hospital,University of Health and Rehabilitation Science.Qingdao 266042,Shandong Province,China)

机构地区：[1]青岛大学附属青岛市海慈医院(青岛市中医医院)口腔科,山东青岛266000 [2]康复大学青岛中心医院(青岛市中心医院)口腔科,山东青岛266042

出　　处：《上海口腔医学》2024年第3期260-264,共5页Shanghai Journal of Stomatology

基　　金：山东省自然科学基金面上项目(ZR202103030420)。

摘　　要：目的:探讨iRoot BP plus与MTA根尖屏障术治疗年轻恒牙慢性根尖周炎的效果。方法:将122例年轻恒牙慢性根尖周炎患者随机分为试验组(n=61,患牙61颗)和对照组(n=61,患牙61颗),试验组行iRoot BP plus根尖屏障术,对照组行MTA根尖屏障术,比较2组患者术后3、6、9、12个月的旧根尖周指数(old periapical index,O-PAI)、根尖透射区面积、疗效、治疗次数、炎症因子水平。采用SPSS 19.0软件包对数据进行统计学分析。结果:术后12个月,试验组和对照组的O-PAI评级为(1.48±0.36)、(1.71±0.42),根尖透射区面积为(0.51±0.14)、(1.09±0.31),2组O-PAI评级和根尖透射区面积相比差异显著(P<0.05)。术后3、6、12个月,2组患者的O-PAI评级逐渐降低(P<0.05),根尖透射区面积逐渐减少(P<0.05)。术后12个月,试验组和对照组的成功率为98.36%、88.52%,组间差异显著(P<0.05)。试验组和对照组患者的治疗次数为(3.64±0.58)、(4.72±0.61)次,组间差异显著(P<0.05)。术后3个月,试验组和对照组患者的血清hs-CRP水平为(6.89±1.13)、(7.25±1.40)mg/L,与治疗前相比差异显著(P<0.05);治疗3个月后,试验组和对照组患者的血清IL-6水平为(82.04±19.62)、(87.52±20.85)mg/L,与治疗前相比差异显著(P<0.05)。2组患者治疗前、后的血清IL-6、hs-CRP水平组间相比,差异无显著性(P>0.05)。结论:iRoot BP plus根尖屏障术治疗年轻恒牙慢性根尖周炎有助于降低O-PAI指数,减少术后就诊次数,术后成功率更高。PURPOSE:To explore the effect of using iRoot BP plus and MTA apical barrier surgery in young permanent teeth with chronic apical periodontitis.METHODS:A total of 122 patients with chronic periapical periodontitis with open root tips of permanent teeth were randomly divided into experimental group(n=61,61 teeth)and a control group(n=61,61 teeth).Patients in the experimental group received iRoot BP plus plus apical barrier surgery,while those in the control group received MTA apical barrier surgery.The old periapical index(O-PAI),apical transmission area,efficacy,treatment times,and inflammatory factor levels of the two groups of patients were compared at 3,6,9,and 12 months after surgery.SPSS 19.0 software package was used for statistical analysis.RESULTS:At 12 months after surgery,the O-PAI ratings of the experimental group and the control group were(1.48±0.36)and(1.71±0.42),respectively,and the apical transmission area was(0.51±0.14)and(1.09±0.31).There was a significant difference in the O-PAI ratings and apical transmission area between the two groups(P<0.05).At 3 months,6 months,and 12 months after surgery,the O-PAI scores of patients in both groups gradually decreased(P<0.05).After 12 months of treatment,the success rates of the experimental group and the control group were 98.36%and 88.52%,respectively,with significant difference between the two groups(P<0.05).The treatment frequency of patients in the experimental group and the control group was(3.64±0.58)times and(4.72±0.61)times,respectively,with a significant difference between the two groups(P<0.05).After 3 months of treatment,the serum hs-CRP levels in the experimental group and the control group were(6.89±1.13)mg/L and(7.25±1.40)mg/L,respectively,with a significant difference compared to pre-treatment(P<0.05).After 3 months of treatment,the serum IL-6 levels in the experimental group and the control group were(82.04±19.62)mg/L and(87.52±20.85)mg/L,respectively,with significant differences compared to pre-treatment(P<0.05).There was no signi

关 键 词：根尖屏障术 iRoot BP plus MTA 年轻恒牙 根尖周炎 

分 类 号：R781.34[医药卫生—口腔医学]