正交法设计乙酸甲酯制备的教学实验  

Orthogonal design for teaching experiment of methyl acetate synthesis

作　　者：莫琰 姚添壹 许怡璇 史津赫 陈彤彤[1,2] 谭大志[1] MO Yan;YAO Tianyi;XU Yixuan;SHI Jinhe;CHEN Tongtong;TAN Dazhi(Experiment Center of Chemistry,Dalian University of Technology,Dalian 116023,China;Green Chemistry Experimental Associations,Dalian University of Technology,Dalian 116023,China)

机构地区：[1]大连理工大学基础化学实验中心,辽宁大连116023 [2]大连理工大学绿色化学实验社团,辽宁大连116023

出　　处：《实验室科学》2024年第3期39-42,共4页Laboratory Science

基　　金：2020年度大连理工大学大学生科研创新训练项目(项目编号:20211014110802);2024年度大连理工大学大学生科研创新训练项目(项目编号:20241014130094);2023年度大连理工大学教育部质量工程项目(项目编号:ZL 2023130)。

摘　　要：介绍了应用正交法设计乙酸甲酯制备教学实验的方法,分析了醇酸摩尔比、催化剂用量、分馏柱长度这三个因素对乙酸甲酯收率的影响,筛选出制备的最佳实验条件为醇酸摩尔比为1.3∶1,催化剂用量为1.5 mL,分馏柱长度30 cm,实现以较少的试验次数达到与全面试验相近的结果。在化学实验教学时,将实验操作训练与数据处理知识相结合,不仅提高了学生的学习兴趣,还让他们更好地理解实验设计思想,培养了他们分析问题和解决问题的实践能力和创新能力,取得了良好的教学效果。This paper introduces the application of orthogonal design for the teaching experiment of methyl acetate synthesis method,analyzes the effects of the molar ratio of alcohol/acid,catalyst dosage,fractionating column length of these three factors on the yield of methyl acetate.The optimum experimental conditions for synthesis are selected as follows:the molar ratio of alcohol/acid is 1.3∶1,catalyst dosage is 1.5 mL and fractionating column is 30 cm in length.And the results are similar to the comprehensive test with less test times.In chemical experiment teaching,the combination of experimental operation training and data processing knowledge not only improves students learning interest,but also enables them to better understand the idea of experimental design,cultivate their practical and innovative ability to analyze and solve problems,and achieve good teaching effects.

关 键 词：正交设计 乙酸甲酯 酯化反应 教学 

分 类 号：G482[文化科学—教育学]