CT引导下肺小结节穿刺活检诊断准确性和真阴性分析  

Analysis of diagnostic accuracy and true negative rate of CT-guided needle biopsy for small pulmonary nodules

作　　者：石冉 武自强 王丽丹 邓克学 王朋[1] SHI Ran;WU Zi-qiang;WANG Li-dan(The First Affiliated Hospital of university of science and technology of china(South District),Heifei 230036,Anhui)

机构地区：[1]中国科学技术大学附属第一医院(南区)影像中心,安徽合肥230036

出　　处：《安徽医专学报》2024年第3期15-17,21,共4页Journal of Anhui Medical College

基　　金：中央高校基金(编号:WK91000015)。

摘　　要：目的:探讨CT引导下对肺小结节(≤20mm)穿刺活检的诊断准确性和真阴性。方法:回顾性分析医院影像中心120例肺部小结节患者接受CT引导下的穿刺活检成功率、诊断准确性和真阴性的数据。结果:穿刺活检成功率100%,120个肺结节的穿刺活检结果包括恶性肿瘤(67例)、疑似恶性肿瘤(4例)、特异性良性病变(8例)和非特异性良性病变(41例);最终诊断包括恶性(87例)、良性(31例)和非诊断性病变(2例);敏感性、特异性和诊断准确率分别为81.6%、100%和87.9%。基于Cox回归分析,真正阴性的显著独立预测因素是慢性炎症伴纤维增生。结论:CT引导下肺小结节穿刺活检具有较高的诊断准确性,慢性炎症伴纤维增生可预测真正的阴性结果。Objective:To analyze the diagnostic accuracy and true negative rate of CT-guided percutaneous biopsy of small pulmonary nodules(≤20 mm).Method:A retrospective analysis was conducted on the success rate,diagnostic accuracy,and true negative data of 120 patients with pulmonary nodules who underwent CT guided biopsy in our center.Result:The success rate was 100%,and the biopsy results of 120 lung nodules included malignant tumors(n=67),suspected malignant tumors(n=4),specific benign lesions(n=8),and non-specific benign lesions(n=41)The final diagnosis includes malignant(n=87),benign(n=31),and non diagnostic lesions(n=2),The sensitivity,specificity,and diagnostic accuracy were 81.6%,100%,and 87.9%,respectively.Based on Cox regression analysis,the significant independent predictor of true negativity is chronic inflammation with fibrosis.Conclusion:CT guided needle biopsy of pulmonary nodules has high diagnostic accuracy,and chronic inflammation with fibrosis can predict true negative results.

关 键 词：计算机断层扫描 肺小结节 穿刺活检 准确率 真阴性 

分 类 号：R734.2[医药卫生—肿瘤]