基于CISS分型急性缺血性脑卒中患者血管内治疗临床分析  

Clinical analysis of intravascular therapy for acute ischemic stroke patients based on CISS classification

作　　者：严银天 施雪英[1] 唐雄伟 方平[1] 曹莉 方国真 YAN Yin-tian;SHI Xue-ying;TANG Xiong-wei(Anqing Medical Center of Anhui Medical University(Fifth Clinical Medical College of Anhui Medical University),Anqing 246000,Anhui)

机构地区：[1]安徽医科大学安庆医学中心(安徽医科大学第五临床医学院),安徽安庆246000

出　　处：《安徽医专学报》2024年第3期18-21,共4页Journal of Anhui Medical College

基　　金：安庆市科技局科研基金项目(编号:2021Z2008)。

摘　　要：目的:对急性缺血性脑卒中(AIS)患者应用CISS分型方法进行亚型分析,对比不同亚型AIS患者应用的不同血管内治疗的预后情况,为AIS患者提供临床有效治疗方案。方法:比较患者入院时、治疗后30d、90d的美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin量表(mRS)评分及日常生活自理能力(ADL)评分。结果:与入院时相比,两亚型AIS患者直接取栓组和桥接治疗组治疗后30d、90d的NHISS评分、mRS评分均低于治疗前,ADL评分显著高于治疗前,差异均有统计学意义(P<0.01)。LAA亚型桥接治疗组治疗后30d、90d的NHISS评分及mRS评分均显著低于直接取栓组,ADL评分均显著高于直接取栓组(P<0.01);CS亚型两组患者治疗后30d、90d的NHISS评分、mRS评分及ADL评分组间比较无明显差异(P>0.05)。结论:LAA亚型AIS患者桥接治疗预后优于直接取栓治疗,CS亚型AIS患者直接取栓与桥接治疗预后未见明显差异。Objective:A subtype analysis of acute ischemic stroke(AIS)patients was performed by applying the CISS typing method to compare the prognosis of different endovascular treatments applied to patients with different subtypes of AIS,so as to provide clinically effective treatment options for AIS patients.Methods:Compare the National Institutes of Health Stroke Scale(NIHSS)scores,Modified Rankin Scale(mRS)scores,and Daily Living Ability(ADL)scores at the time of admission,30 days,and 90 days after treatment.Results:Compared with admission,the NHISS scores and mRS scores of patients with both subtypes of AIS in the direct thrombolysis group and the bridging treatment group were lower than those before treatment at 30 and 90 days after treatment,and the ADL scores were significantly higher than those before treatment,and the differences were statistically significant(P<0.01).The NHISS scores and mRS scores at 30 and 90 days after treatment in the LAA subtype bridging treatment group were significantly lower than those in the direct bolus extraction group,and the ADL scores were significantly higher than those in the direct bolus extraction group(P<0.01);there was no significant difference in the NHISS scores,mRS scores,and ADL scores between groups of the two groups of patients in the CS subtype at 30 and 90 days after treatment(P>0.05).Conclusion:The prognosis of bridging therapy was better than direct thrombolysis in patients with LAA subtype AIS,and no significant difference in prognosis was seen between direct thrombolysis and bridging therapy in patients with CS subtype AIS.

关 键 词：急性缺血性脑卒中 CISS分型 直接取栓 桥接治疗 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]