单孔胸腔镜肺癌根治术联合阶梯性镇痛干预在肺癌患者中的应用效果  

Application effect of single-port thoracoscopic radical resection of lung cancer combined with stepped analgesia intervention in patients with lung cancer

作　　者：孙郑华 刘玉荣[1] 陈静儒 李珊珊[1] 杨慧[1] SUN Zhenghua;LIU Yurong;CHEN Jingru;LI Shanshan;YANG Hui(Department of Thoracic Surgery,He’nan Provincial People’sHospital,Zhengzhou 450000,He’nan,China)

机构地区：[1]河南省人民医院胸外科,郑州4500000

出　　处：《癌症进展》2024年第10期1127-1130,共4页Oncology Progress

摘　　要：目的探讨单孔胸腔镜肺癌根治术联合阶梯性镇痛干预在肺癌患者中的应用效果。方法将210例肺癌患者根据干预方式的不同分为常规组(n=100)和镇痛组(n=110),两组患者均行单孔胸腔镜肺癌根治术,常规组患者围手术期接受常规干预,镇痛组患者围手术期接受阶梯性镇痛干预。比较两组患者的术后指标、镇痛情况、肺功能指标[最大自主通气量(MVV)、用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))]、疼痛程度[视觉模拟评分法(VAS)]、认知功能[简易智力状态检查量表(MMSE)]及满意情况。结果镇痛组患者首次下床时间、引流管留置时间均明显短于常规组,镇痛药物使用率明显低于常规组,总满意率明显高于常规组,差异均有统计学意义(P﹤0.01)。干预后2天,两组患者FVC、MVV、FEV_(1)及VAS评分均低于本组干预前1天,MMSE评分高于本组干预前1天,镇痛组患者FVC、MVV、FEV_(1)及MMSE评分均高于常规组,VAS评分低于常规组,差异均有统计学意义(P﹤0.05)。结论单孔胸腔镜肺癌根治术联合阶梯性镇痛干预可以促进肺癌患者术后恢复,有效减轻患者疼痛,改善患者认知状态及肺功能,提高患者的满意度。Objective To investigate the application effect of single-port thoracoscopic radical resection of lung can-cer combined with stepped analgesia intervention in patients with lung cancer.Method A total of 210 patients with lung cancer were divided into conventional group(n=100)and analgesic group(n=110)according to different intervention methods.All patients underwent single-port thoracoscopic radical resection of lung cancer,the conventional group received conventional intervention during perioperative period,the analgesic group received stepped analgesic intervention during perioperative period.The postoperative indexes,analgesia,pulmonary function indexes[maximal voluntary venti-lation(MVV),forced vital capacity(FVC),forced expiratory volume in one second(FEV_(1))],pain[visual analogue scale(VAS)],cognitive function[mini-mental state examination(MMSE)]and satisfaction were compared between the two groups.Result The first time of getting out of bed and the time of drainage tube placement in the analgesic group were significantly shorter than those in the conventional group,the utilization rate of analgesic drugs was significantly lower than that in the conventional group,the total satisfaction rate was significantly higher than that in the conventional group,and the differences were statistically significant(P<0.01).Two days after intervention,the FVC,MVV,FEV_(1) and VAS scores in two groups were lower than those one day before intervention,the MMSE scores were higher than those one day before intervention,the FVC,MVV,FEV_(1) and MMSE score in analgesic group were higher than those in convention-al group,the VAS score was lower than that in conventional group,and the differences were statistically significant(P<0.05).Conclusion Single-port thoracoscopic radical resection of lung cancer combined with stepped analgesia interven-tion can promote postoperative recovery of lung cancer patients,effectively reduce pain of patients,improve cognitive sta-tus,pulmonary function and satisfaction rate of patients.

关 键 词：肺癌 单孔胸腔镜 肺癌根治术 阶梯性镇痛干预 效果 

分 类 号：R734.2[医药卫生—肿瘤]