基于腹部CT确定腹部脂肪参数与肠系膜脂膜炎的关系  

Study on the correlation between abdominal fat parameters determined based on abdominal CT and mesenteric panniculitis

作　　者：吴雯[1] 王伟浪 吉欣 陈洪[1] WU Wen;WANG Weilang;JI Xin;CHEN Hong(Department of Gastroenterology,Zhongda Hospital,Southeast University,Nanjing,Jiangsu 210009,China;Department of Imaging,Zhongda Hospital,Southeast University,Nanjing,Jiangsu 210009,China)

机构地区：[1]东南大学附属中大医院消化科,江苏南京210009 [2]东南大学附属中大医院影像科,江苏南京210009

出　　处：《徐州医科大学学报》2024年第5期357-362,共6页Journal of Xuzhou Medical University

摘　　要：目的基于CT测量腹部脂肪参数,探讨肠系膜脂膜炎(MP)与肥胖之间的关系。方法对2019年8月—2022年7月在东南大学附属中大医院住院行腹部CT检查的患者进行回顾性匹配对照研究,根据放射学标准诊断为MP的患者为MP组。收集研究对象的基线信息和血脂水平,获取L3椎体水平上的CT图像,基于腹部CT图像,应用Image J软件测量腹部脂肪参数,使用单因素和多因素分析研究体重指数(BMI)、血脂水平及腹部脂肪参数与MP之间的关系。根据患者BMI和内脏脂肪面积(VFA),分为BMI正常组、内脏型肥胖组、非内脏型肥胖组,比较3组间MP患病率及影像学特征的差异。结果在905例CT诊断为MP的患者中,242例被纳入研究。MP组VFA为(172.46±73.74)cm^(2),皮下脂肪面积(SFA)为(149.54±57.59)cm^(2),VFA/SFA为1.25±0.61。MP组BMI、VFA、SFA和VFA/SFA均明显高于对照组(P<0.05),而2组间血脂水平差异无统计学意义,多因素分析发现BMI、VFA是MP的独立危险因素。MP患病率在不同肥胖类型之间有差异,内脏型肥胖、非内脏型肥胖者患MP的风险分别为BMI正常者的3.83、2.08倍。结论肥胖在MP的发病中起到一定作用,其中VFA升高与MP发病有关,内脏型肥胖、非内脏型肥胖均为MP的危险因素。Objective To explore the relationship between mesenteric panniculitis(MP)and obesity based on abdominal fat parameters measured by CT.Methods A retrospective matched case-control study was conducted on patients diagnosed with MP according to radiologic criteria who underwent abdominal CT from August 2019 to July 2022 at Zhongda Hospital affiliated with Southeast University.Baseline information and blood lipids of the participants were collected,and CT images at the level of the L3 vertebra were obtained.Abdominal fat parameters were measured based on abdominal CT images using Image J software,and the association between body mass index(BMI),lipid levels,and abdominal fat parameters with MP was investigated using univariate and multivariate analysis.According to the patients′BMI and visceral fat area(VFA),subjects were divided into normal BMI,visceral obesity,and non-visceral obesity groups,and the prevalence of MP was compared among the three groups,as well as their differences in MP imaging characteristics.Results Among 905 patients diagnosed with MP by CT,242 were included in the study.The VFA in the case group was(172.46±73.74)cm^(2),the subcutaneous fat area(SFA)was(149.54±57.59)cm^(2),and the VFA/SFA ratio was 1.25±0.61.Compared to the control group,the BMI,VFA,SFA and VFA/SFA in the MP group were significantly higher(P<0.05),while there was no statistically significant difference in lipid levels between the two groups.Multifactorial logistic regression analysis showed that BMI and VFA were independent risk factors for MP.The prevalence of MP differed among different obesity types,with visceral and non-visceral obese individuals having 3.83 and 2.08 times the risk of developing MP,respectively,compared to those with normal body weight.Conclusions Obesity plays a certain role in the etiology of MP,with an increased in visceral fat area being associated with the onset of MP.Both visceral and non-visceral obesity are risk factors for MP.

关 键 词：肠系膜脂膜炎 肥胖 超重 内脏脂肪 皮下脂肪 计算机断层扫描 

分 类 号：R572.3[医药卫生—消化系统]