甲状腺微小乳头状癌的术中冰冻病理诊断探讨  

Intraoperative Frozen Pathological Diagnosis of Thyroid Micropapillary Carcinoma

作　　者：李军 许研 卓倩 LI Jun;XU Yan;ZHUO Qian(Department of Pathology,Huai'an Hospital,Huai'an,Jiangsu Province,223200 China)

机构地区：[1]江苏省淮安市淮安医院病理科,江苏淮安223200

出　　处：《系统医学》2024年第10期46-48,共3页Systems Medicine

摘　　要：目的探索术中冷冻病理切片在乳头状甲状腺癌诊断中的价值。方法选取2019年1月—2022年5月江苏省淮安市淮安医院收治的120例疑似甲状腺微小乳头状癌患者为研究对象,均实施术中冰冻病理切片检查、术后石蜡切片检查,以术后石蜡切片检查结果为金标准,分析术中病理切片检查的检出情况、诊断效能。结果以石蜡切片术后检查为金标准,术中冷冻病理切片检出率为99.08%,灵敏度为97.25%、特异度为81.82%、阳性预测值为98.15%、阴性预测值为75.00%、准确率为95.83%,kappa值为0.760(P<0.05)。结论术中冷冻病理切片在乳头状甲状腺癌诊断中具有较高的准确率,可明确疾病类型,以便及时调整手术方案,达到改善预后效果的目的,值得借鉴。Objective To explore the value of intraoperative frozen pathological sections in the diagnosis of papillary thyroid carcinoma.Methods A total of 120 patients with suspected thyroid micropapillary carcinoma admitted to Huai'an Hospital,Jiangsu Province from January 2019 to May 2022 were selected as the study objects.All of them un⁃derwent intraoperative frozen pathological section examination and postoperative paraffin section examination.The re⁃sults of postoperative paraffin section examination were used as the gold standard to analyze the detection and diagnos⁃tic efficiency of intraoperative pathological section examination.Results Paraffin section postoperative examination was used as the gold standard,the detection rate of intraoperative frozen pathological section was 99.08%,sensitivity was 97.25%,specificity was 81.82%,positive predictive value was 98.15%,negative predictive value was 75.00%,ac⁃curacy was 95.83%,and kappa value was 0.760(P<0.05).Conclusion Intraoperative frozen pathological sections have a high accuracy in the diagnosis of papillary thyroid cancer,which can identify the type of the disease,so as to adjust the surgical plan in time and achieve the purpose of improving the prognosis.

关 键 词：甲状腺 微小乳头状癌 术中冰冻病理 诊断 术后石蜡切片 直径 

分 类 号：R736.1[医药卫生—肿瘤]