静心止动方治疗儿童抽动障碍脾虚肝旺证临床观察  

Jingxin Zhidong Prescription in the Treatment of Tic Disorder of Children with Spleen Deficiency and Liver Hyperactivity Type

作　　者：刘来 王亮[1] 董燕[2] 王亚哲[3] 赵方圆 赵庆贺[4] LIU Lai;WANG Liang;DONG Yan;WANG Yazhe;ZHAo Fangyuan;ZHAO Qinghe(Department of Traditional Chinese Medicine,The Third Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China;Department of Pediatrics,The Third Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China;Child Developmental Behavior Clinic,The Third Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China;Department of Pharmacy,The Third Affiliated Hospital of Zhengzhou University,Henan Province,Zhengzhou 450052,China)

机构地区：[1]郑州大学第三附属医院中医科,河南郑州450052 [2]郑州大学第三附属医院儿科,河南郑州450052 [3]郑州大学第三附属医院儿童发育行为科,河南郑州450052 [4]郑州大学第三附属医院药学部,河南郑州450052

出　　处：《光明中医》2024年第12期2331-2334,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：中国妇幼保健协会-华润三九专项研究基金项目(No.ZXY2020A04)。

摘　　要：目的 观察静心止动方治疗儿童抽动障碍脾虚肝旺证的临床疗效。方法 选取2019年9月—2023年6月就诊于郑州大学第三附属医院的抽动障碍患儿103例,分为对照组52例和观察组51例。对照组予硫必利口服,观察组予中药静心止动方口服,疗程均为4周。观察2组患儿YGTSS评分、中医证候积分及TESS总分。结果 对照组总有效率低于观察组,差异无统计学意义(P>0.05)。治疗后,2组患儿YGTSS评分、中医证候积分均较治疗前显著减少(P<0.05),且观察组中医证候改善优于对照组(P<0.05),TESS总分低于对照组(P<0.05)。结论 静心止动方治疗儿童抽动障碍脾虚肝旺证疗效满意,有助于改善患儿的抽动症状和中医证候,且安全性高,值得临床推广。Objective To observe the clinical effect of Jingxin Zhidong prescription on tic disorder(TD)in children with spleen deficiency and liver hyperactivity type.Methods A total of 103 TD children in The Third Affiliated Hospital of Zhengzhou University from September 2019 to June 2023 were selected and divided into control group of 52 cases and observation group of 51 cases.The control group was given Tiapride orally,and the observation group was given Jingxin Zhidong prescription orally,the course of treatment was 4 weeks.YGTSS score,TCM syndrome score and TESS total score of the two groups were observed.ResultsAfter the treatment course,the total effective rate of the observation group was higher than that of the centrol group,and the difference was not statistically significant(P>0.05).The YCTSS score and TCM symptom score of the two groups were significantly reduced compared with that before treatment(P<0.05),and the improvement of TCM syndrome in the observation group was better than that in the control group(P<0.05),while the TESS total score was lower than that in the control group(P<0.05).Conclusion Jingxin Zhidong prescription has satisfactory efficacy in the treatment of TD in children with spleen deficiency and liver hyperactivity type,which is helpful to improve the tic symptoms and the TCM syndromes of children,it is safe and worthy of clinical promotion.

关 键 词：慢惊风 抽动障碍 脾虚肝旺证 静心止动方 硫必利 

分 类 号：R277.7[医药卫生—中医学]