焦虑障碍的脑电生理研究进展  

Research progress of eletroencephalography in anxiety disorders

作　　者：袁丹凤 杨祥云[1] 李占江[1] Yuan Danfeng;Yang Xiangyun;Li Zhanjiang(Beijing Key Laboratory of Mental Disorders,National Clinical Research Center for Mental Disorders,Beijing Anding Hospital,Capital Medical University,Beijing 100088,China)

机构地区：[1]首都医科大学附属北京安定医院、国家精神心理疾病临床医学研究中心、精神疾病诊断与治疗北京市重点实验室,100088

出　　处：《神经疾病与精神卫生》2024年第6期423-428,共6页Journal of Neuroscience and Mental Health

基　　金：科技创新2030-“脑科学与类脑研究”重大项目(2021ZD0202004);首都卫生发展科研专项重点攻关项目(2020-1-2121)。

摘　　要：焦虑障碍临床表现复杂,目前缺乏诊断以及疗效预测相关的神经生物学指标。脑电图是一种非侵入性的神经电生理检测工具,具有较高的时间分辨率,能锁时反映焦虑障碍认知损害的时间进程。现对焦虑障碍的时域、频域、功能连接脑电特征的相关研究进行综述,探索焦虑障碍自上而下和自下而上的认知加工异常,为进一步明确焦虑障碍的神经心理机制以及探索焦虑障碍预测、诊断、预后相关的神经生物学客观指标提供参考。The clinical manifestations of anxiety disorders are complex,and there is currently a lack of neurobiological indicators related to diagnosis and efficacy prediction.Electroencephalogram(EEG)is a non-invasive neurophysiological detection tool with high temporal resolution,which can reflect the temporal progression of cognitive impairment in anxiety disorders.This article reviews the relevant research on the temporal,frequency,and functional connectivity EEG characteristics of anxiety disorders,exploring the cognitive processing abnormalities of anxiety disorders from top-down and bottom-up.The aim of this review was to provide reference for further clarifying the neuropsychological mechanisms of anxiety disorders and exploring objective neurobiological indicators related to the prediction,diagnosis,and prognosis of anxiety disorders.

关 键 词：焦虑障碍 脑电图 脑电描记术 综述 

分 类 号：R749[医药卫生—神经病学与精神病学]