植物类黄酮转运与积累机制的研究进展  

Advances in Plant Flavonoid Transport and Accumulation Mechanism

作　　者：谢靖雯 曹晓云 潘婉琪 杜灵娟 Jingwen Xie;Xiaoyun Cao;Wanqi Pan;Lingjuan Du(College of Landscape Architecture and Arts,Northwest A&F University,Yangling 712100,China;Key Laboratory of Horticultural Plant Biology and Germplasm Innovation in Northwest China,Ministry of Agriculture/State Key Laboratory of Crop Stress Biology for Arid Areas(Northwest A&F University),Yangling 712100,China)

机构地区：[1]西北农林科技大学风景园林艺术学院,杨凌712100 [2]旱区作物逆境生物学国家重点实验室(西北农林科技大学)/农业部西北地区园艺作物生物学与种质创制重点实验室,杨凌712100

出　　处：《植物学报》2024年第3期463-480,共18页Chinese Bulletin of Botany

基　　金：国家自然科学基金(No.32171863,No.31700625);西安市科技计划(No.22NYYF005)。

摘　　要：类黄酮是植物次生代谢过程中产生的多酚类物质,在植物中广泛存在且功能多样。类黄酮的生物合成发生在内质网的细胞质侧,但最终积累在液泡腔内。因此,需要高效的类黄酮转运和积累系统将其从内质网转移至液泡内。几十年来,关于植物类黄酮转运有诸多研究。目前的研究结果表明,植物体内存在3种类黄酮转运机制,包括谷胱甘肽转移酶介导的转运及膜转运蛋白和囊泡介导的转运。该文综述了这3种转运机制以及近年来植物类黄酮转运研究进展,分析总结了3种不同但具有非排它性机制在功能上的协同作用。虽然类黄酮生物合成途径在许多物种中得到很好的表征,但是关于其转运研究仍相对缺乏。类黄酮修饰与转运的关系、转运蛋白对底物的特异性和偏好性及类黄酮转运的转录调控仍需深入探索,以更好地解析类黄酮在植物细胞中的转运和积累机制。Flavonoids are polyphenols compounds produced during the secondary metabolism of plants,which are widely present in plants and have various functions.Flavonoids biosynthesis takes place at the cytosolic side of the endoplasmic reticulum(ER),but accumulation of various flavonoids is observed in the vacuole.Efficient transport and accumulation systems are therefore required to transfer flavonoids from the ER into the vacuole.Certain researches for the transport of flavonoids has been done for decades.Current research results showed that:there are three transport mechanisms in plants,including glutathione S-transferase(GST),membrane transporters,and vesicle trafficking.Here,we reviewed the three transport mechanisms and advances of plant flavonoids transport in recent years.The functional cooperation of three distinct but nonexclusive mechanisms were summarized.While the biosynthesis of the flavonoids is well characterized across species,the research on flavonoids transport and accumulation is still relatively insufficient.For better understand the flavonoids transport and accumulation mechanism in plant,the relationship between flavonoids modification and transport,flavonoids transport substrate specificity and preference,and transcriptional regulation of flavonoids transport remain deeply unexplored.

关 键 词：类黄酮 转运 谷胱甘肽转移酶 膜转运蛋白 囊泡转运 

分 类 号：Q945[生物学—植物学]